Evidence map›Paper›PMID 37534363›Full record

ArticleFrontiers in physiology2023

Regulation of human salt-sensitivite hypertension by myeloid cell renin-angiotensin-aldosterone system.

Lale A Ertuglu, Ashley Pitzer Mutchler, Fernando Elijovich, Cheryl L Laffer, Quanhu Sheng, Celestine N Wanjalla, Annet Kirabo

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07602166 (Effect of an Isolevuglandin Scavenger on Salt Sensitivity of Blood Pressure and Immune Cell Activation in Humans), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07602166 phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effect of an Isolevuglandin Scavenger on Salt Sensitivity of Blood Pressure and Immune Cell Activation in Humans

TypeinterventionalSponsorVanderbilt University Medical CenterRan2026 to 2031Enrolled20ConditionsSalt Sensitivity of Blood Pressure, High Blood Pressure, Inflammation, Renin-Angiotensin-Aldosterone SystemArms2-hydroxybenzylamine, Placebo
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lale A ErtugluDepartment of Medicine, Division of Nephrology, Vanderbilt University Medical Center, Nashville, TN, United States.
Ashley Pitzer MutchlerDepartment of Medicine, Division of Clinical Pharmacology, Vanderbilt University Medical Center Nashville, Nashville, TN, United States.
Fernando ElijovichDepartment of Medicine, Division of Clinical Pharmacology, Vanderbilt University Medical Center Nashville, Nashville, TN, United States.
Cheryl L LafferDepartment of Medicine, Division of Clinical Pharmacology, Vanderbilt University Medical Center Nashville, Nashville, TN, United States.
Quanhu ShengDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, United States.
Celestine N WanjallaDepartment of Internal Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center Nashville, Nashville, TN, United States.
Annet KiraboDepartment of Medicine, Division of Clinical Pharmacology, Vanderbilt University Medical Center Nashville, Nashville, TN, United States.
Vanderbilt University Medical Center · US

Funding

Tennessee CFAR: Implementation of Culturally Responsive Trauma-Informed Care with Youth with HIV in Memphis, TNP30AI110527 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI John Koethe · 2015 to 2026
$27.5M
Training In Cardiovascular Physiology & PharmacologyT32HL007444 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ju Chen, Robert Scott Ross · 1985 to 2026
$11.1M
UCSD PRIDE Faculty Development Program in Cardiovascular SciencesR25HL145817 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Robert Scott Ross, Joann Trejo · 2019 to 2026
$3.3M
NHLBI NIH HHS R25 HL145817NHLBI NIH HHS T32 HL007444NIAID NIH HHS P30 AI110527
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

hypertensionimmunitymyeloid immune cellsrenin-angiotensin-aldosterone systemsalt sensitivity

Identifiers

PMID37534363
PMCPMC10390697
OpenAlexW4384694930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.