Evidence map›Paper›PMID 37534171›Full record

ArticleiScience2023

Lipid metabolism dysfunction following symbiont elimination is linked to altered Kennedy pathway homeostasis.

Geoffrey M Attardo, Joshua B Benoit, Veronika Michalkova, Alekhya Kondragunta, Aaron A Baumann, Brian L Weiss, Anna Malacrida, Francesca Scolari, Serap Aksoy

Open access · goldAbstract read
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Function ofInsects · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. mir-31 mediated control of bacteriome size in tsetse flies.Current research in insect science · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Geoffrey M AttardoDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
Joshua B BenoitDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
Veronika MichalkovaDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
Alekhya KondraguntaDepartment of Biological Sciences, University of Cincinnati, Cincinnati, OH 45221, USA.
Aaron A BaumannDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
Brian L WeissDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
Anna MalacridaDepartment of Biology and Biotechnology, University of Pavia, 27100 Pavia, Italy.
Francesca ScolariDepartment of Biology and Biotechnology, University of Pavia, 27100 Pavia, Italy.
Serap AksoyDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
Yale University · USUniversity of Cincinnati · USIstituto di Genetica Molecolare · ITSlovak Academy of Sciences · SKUniversity of California, Davis · USUniversity of Pavia · IT

Funding

Molecular Aspects of Tsetse and Trypanosome TransmissionR01AI051584 · NIAID · YALE UNIVERSITY · PI AKSOY, SERAP · 2003 to 2013
$4.3M
Trypanosome Transmission Biology in TsetseR01AI158805 · NIAID · YALE UNIVERSITY · PI Serap AKSOY · 2022 to 2026
$4.1M
Molecular Aspects of Tsetse and Trypanosome TransmissionR01AI139525 · NIAID · YALE UNIVERSITY · PI AKSOY, SERAP · 2019 to 2024
$4.1M
Mosquito hydration status as a mechanism that alters pre-feeding host interactions and post-feeding physiologyR01AI148551 · NIAID · UNIVERSITY OF CINCINNATI · PI BENOIT, JOSH B., XIAO, YANYU · 2020 to 2024
$2.1M
Tsetse Fecundity Reduction for Trypanosomiasis ControlR01AI081774 · NIAID · YALE UNIVERSITY · PI AKSOY, SERAP · 2009 to 2013
$2.0M
tRNA modifications as critical components of insect blood feeding and reproductionR21AI176098 · NIAID · UNIVERSITY OF CINCINNATI · PI BENOIT, JOSH B., LIMBACH, PATRICK A · 2023 to 2024
$446k
Spiroplasma effects on Tsetse FliesR21AI163969 · NIAID · YALE UNIVERSITY · PI AKSOY, SERAP, WEISS, BRIAN L · 2021 to 2022
$430k
Influence of sleep-like states on mosquito behavior and physiologyR21AI166633 · NIAID · UNIVERSITY OF CINCINNATI · PI BENOIT, JOSH B., VINAUGER, CLEMENT · 2022 to 2023
$429k
Expanding the toolbox for tsetse reproductive biologyR21AI109263 · NIAID · YALE UNIVERSITY · PI AKSOY, SERAP, ATTARDO, GEOFFREY M · 2014 to 2015
$428k
Unraveling Intersexual Interactions in TsetseR21AI128523 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ATTARDO, GEOFFREY M · 2018 to 2019
$406k
Lipid metabolism during tsetse reproductionF32AI093023 · NIAID · YALE UNIVERSITY · PI BENOIT, JOSH B. · 2011 to 2013
$114k
NIAID NIH HHS F32 AI093023NIAID NIH HHS R01 AI051584NIAID NIH HHS R01 AI081774NIAID NIH HHS R01 AI139525NIAID NIH HHS R01 AI148551NIAID NIH HHS R01 AI158805NIAID NIH HHS R21 AI109263NIAID NIH HHS R21 AI128523NIAID NIH HHS R21 AI163969NIAID NIH HHS R21 AI166633NIAID NIH HHS R21 AI176098
6 · The paper itself

Abstract

Lipid metabolism is critical for insect reproduction, especially for species that invest heavily in the early developmental stages of their offspring. The role of symbiotic bacteria during this process is understudied but likely essential. We examined the role of lipid metabolism during the interaction between the viviparous tsetse fly (

Indexed as

BacteriologyPhysiology

Identifiers

PMID37534171
PMCPMC10391724
OpenAlexW4380360200

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.