Evidence map›Paper›PMID 37533841›Full record

ArticleBeilstein journal of nanotechnology2023

Nanostructured lipid carriers containing benznidazole: physicochemical, biopharmaceutical and cellular in vitro studies.

Giuliana Muraca, María Esperanza Ruiz, Rocío C Gambaro, Sebastián Scioli-Montoto, María Laura Sbaraglini, Gisel Padula, José Sebastián Cisneros, Cecilia Yamil Chain, Vera A Álvarez, Cristián Huck-Iriart and 6 more

Open access · diamondAbstract read
In one paragraph

Article in Beilstein journal of nanotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Nanomedicines against Chagas disease: a critical review.Beilstein journal of nanotechnology · 2024
    Review
  7. When nanomedicines meet tropical diseases.Beilstein journal of nanotechnology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Giuliana MuracaSee end of main text.ORCID https://orcid.org/0000-0002-4785-8050
María Esperanza RuizSee end of main text.ORCID https://orcid.org/0000-0001-8617-667X
Rocío C GambaroSee end of main text.
Sebastián Scioli-MontotoSee end of main text.ORCID https://orcid.org/0000-0003-3314-3406
María Laura SbaragliniSee end of main text.ORCID https://orcid.org/0000-0002-4671-2658
Gisel PadulaSee end of main text.
José Sebastián CisnerosSee end of main text.ORCID https://orcid.org/0000-0001-7563-978X
Cecilia Yamil ChainSee end of main text.ORCID https://orcid.org/0000-0002-8234-0556
Vera A ÁlvarezSee end of main text.ORCID https://orcid.org/0000-0002-4909-4592
Cristián Huck-IriartSee end of main text.
Guillermo R CastroSee end of main text.ORCID https://orcid.org/0000-0002-6187-7805
María Belén PiñeroSee end of main text.ORCID https://orcid.org/0009-0004-4431-368X
Matias Ildebrando MarchettoSee end of main text.
Catalina Alba SotoSee end of main text.ORCID https://orcid.org/0000-0002-2724-0421
Germán A IslanSee end of main text.
Alan TaleviSee end of main text.ORCID https://orcid.org/0000-0003-3178-826X
Textron Systems (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chagas disease is a neglected endemic disease prevalent in Latin American countries, affecting around 8 million people. The first-line treatment, benznidazole (BNZ), is effective in the acute stage of the disease but has limited efficacy in the chronic stage, possibly because current treatment regimens do not eradicate transiently dormant

Indexed as

benznidazolebiopharmaceutical studyChagas diseasenanoparticlesnanostructured lipid carriersphysicochemical characterizationTrypanosoma cruzi

Identifiers

PMID37533841
PMCPMC10390827
OpenAlexW4385348734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.