Evidence map›Paper›PMID 37533815›Full record

ArticleDrug and alcohol dependence reports2023

Vesicular glutamate transporter 2 expression in the ventral tegmental area of outbred male rats following exposure to nicotine and alcohol.

Maria Vrettou, Stefan Bernhard Thalhammer, Anne-Lie Svensson, Sylvie Dumas, Kent W Nilsson, Åsa Wallén-Mackenzie, Robert Fredriksson, Ingrid Nylander, Erika Comasco

Abstract read
In one paragraph

Article in Drug and alcohol dependence reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maria VrettouDepartment of Women's and Children's Health, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Stefan Bernhard ThalhammerDepartment of Women's and Children's Health, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Anne-Lie SvenssonDepartment of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.
Sylvie DumasOramacell, Paris, France.
Kent W NilssonCentre for Clinical Research Västerås, Uppsala University, Västmanland County Hospital Västerås, Sweden.
Åsa Wallén-MackenzieDepartment of Organismal Biology, Uppsala University, Uppsala, Sweden.
Robert FredrikssonDepartment of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.
Ingrid NylanderDepartment of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.
Erika ComascoDepartment of Women's and Children's Health, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Initiation of use/co-use of nicotine and alcohol, commonly occurring in an episodic manner during adolescence, can imprint vulnerability to the developing brain and lead to addiction. The ventral tegmental area (VTA) is a key heterogeneous region of the mesocorticolimbic circuit involved in the binge-drinking and intoxication step of the addiction circuit. Higher human post-mortem VTA expression of Methods: The present study aimed to map and characterize the Results: The profile of neurons varied with substance-exposure among VTA subregions. Conclusions: VTA

Indexed as

alcoholbrainexpressionnicotineVglut2

Identifiers

PMID37533815
PMCPMC10391930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.