Evidence map›Paper›PMID 37533553›Full record

ArticleIJID regions2023

Respiratory viruses in rural Zambia during the second year of the COVID-19 pandemic.

Catherine G Sutcliffe, Mutinta Hamahuwa, Evan Miller, Pamela Sinywimaanzi, Justin Hardick, Juliet Morales, Passwell Munachoonga, Mwaka Monze, Yukari C Manabe, Katherine Z J Fenstermacher and 4 more

Open access · goldAbstract read
In one paragraph

Article in IJID regions, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Catherine G SutcliffeJohns Hopkins University Bloomberg School of Public Health, Department of Epidemiology, Baltimore, USA.
Mutinta HamahuwaMacha Research Trust, Choma, Zambia.
Evan MillerJohns Hopkins University School of Medicine, Division of Infectious Diseases, Baltimore, USA.
Pamela SinywimaanziMacha Research Trust, Choma, Zambia.
Justin HardickJohns Hopkins University School of Medicine, Division of Infectious Diseases, Baltimore, USA.
Juliet MoralesJohns Hopkins University Bloomberg School of Public Health, Department of International Health, Baltimore, USA.
Passwell MunachoongaMacha Research Trust, Choma, Zambia.
Mwaka MonzeUniversity Teaching Hospital, Virology Laboratory, Lusaka, Zambia.
Yukari C ManabeJohns Hopkins University School of Medicine, Division of Infectious Diseases, Baltimore, USA.
Katherine Z J FenstermacherJohns Hopkins University School of Medicine, Department of Emergency Medicine, Baltimore, USA.
Richard E RothmanJohns Hopkins University School of Medicine, Department of Emergency Medicine, Baltimore, USA.
Andrew PekoszJohns Hopkins University School of Medicine, Division of Infectious Diseases, Baltimore, USA.
Philip E ThumaMacha Research Trust, Choma, Zambia.
Edgar SimulunduMacha Research Trust, Choma, Zambia.
Johns Hopkins University · USGolden Valley Agricultural Research Trust · ZMUniversity Teaching Hospital · ZM

Funding

NIAID NIH HHS HHSN272201400007C
6 · The paper itself

Abstract

Objectives: Limited data on respiratory infections are available from sub-Saharan Africa during the COVID-19 pandemic. The objective of this study was to evaluate the burden of respiratory viruses in rural Zambia from 2019-2021. Methods: Surveillance was initiated at Macha Hospital in Zambia in December 2018. Each week, patients with respiratory symptoms were enrolled from the outpatient clinic. Nasopharyngeal samples were collected and tested for respiratory pathogens. The prevalence of respiratory symptoms and viruses in 2021 was compared to results from 2019 and 2020. Results: After seeing few cases of influenza virus and respiratory syncytial virus in 2020, a return to prepandemic levels was observed in 2021. Rhinovirus/enterovirus, parainfluenza virus 1-4, and adenovirus circulated from 2019 to 2021, while human metapneumovirus and human coronaviruses (HKU1, 229E, OC43, and NL63 subtypes) were observed sporadically. SARS-CoV-2 was observed consistently in 2021 after being first identified in December 2020. The proportion of participants with co-infections in 2021 (11.6%) was significantly higher than in 2019 (6.9%) or 2020 (7.7%). Conclusion: Declines in influenza virus and respiratory syncytial virus were reversed once public health measures were lifted. Respiratory viruses contributed to a significant burden of respiratory infections in 2021. This study provides important information about respiratory viruses in this changing context and underrepresented region.

Indexed as

AfricaInfluenzaRespiratory infectionsRespiratory syncytial virusSARS-CoV-2Surveillance

Identifiers

PMID37533553
PMCPMC10391682
OpenAlexW4384025595

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.