ArticleActa obstetricia et gynecologica Scandinavica2023
Initial establishment and validation of a predictive model for preeclampsia in twin pregnancies based on maternal characteristics and echocardiographic parameters.
Article in Acta obstetricia et gynecologica Scandinavica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 5 citations in OpenAlex.
- Attenuated Impact of Gestational Diabetes Mellitus (GDM) With Hypertensive Disorders of Pregnancy (HDP) on Adverse Pregnancy Outcomes in Twin Versus Singleton Gestations: A Single-Center Real-World Study.Journal of diabetes research · 2026Article
- Longitudinal assessment of maternal echocardiographic changes in singleton versus twin pregnancies and their association with preeclampsia risk.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Article
- Initial establishment and validation of a predictive model for preeclampsia in twin pregnancies based on maternal characteristics and echocardiographic parameters.Acta obstetricia et gynecologica Scandinavica · 2023Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
introductionThe primary objective of this study was to evaluate the association between maternal echocardiographic changes and the occurrence of preeclampsia (PE) in twin pregnancies. Additionally, we established and validated a prediction model for PE in twin pregnancies. MATERIAL AND
methodsThe first part of this study was retrospective and included data from 854 twin pregnancies that received antenatal care at Peking University Third Hospital from April 2017 to April 2021 (training cohort). Overall, 159 women who underwent transthoracic echocardiography were included in the analysis. To build a predictive model, cardiac findings were compared between normotensive women and those with PE. The model was then validated in a prospective longitudinal cohort (test cohort) that included 109 women with twin pregnancies who underwent two consecutive transthoracic echocardiography examinations during the second and third trimesters.
resultsFifty-four normotensive women and 105 women with PE were analyzed in the retrospective cohort that was used to build the model in which later preeclampsia was associated with higher left ventricular mass index (>61 g/m
conclusionsMaternal echocardiographic changes in twin pregnancies are associated with the development of preeclampsia. The model constructed, based on the echocardiographic parameters and body mass index, provides novel ideas for the prediction of PE.
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