Evidence map›Paper›PMID 37533229›Full record

ArticlePsychogeriatrics : the official journal of the Japanese Psychogeriatric Society2023

Gender and age influence the association between gait speed and mild cognitive impairment in community-dwelling Japanese older adults: from the Japan Prospective Studies Collaboration for Ageing and Dementia (JPSC-AD).

Shogyoku Bun, Kouta Suzuki, Hidehito Niimura, Ryo Shikimoto, Hisashi Kida, Mao Shibata, Takanori Honda, Tomoyuki Ohara, Jun Hata, Shigeyuki Nakaji and 8 more

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In one paragraph

Article in Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Shogyoku BunDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Kouta SuzukiDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Hidehito NiimuraDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Ryo ShikimotoDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Hisashi KidaDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Mao ShibataCentre for Cohort Studies, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Takanori HondaCentre for Cohort Studies, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Tomoyuki OharaDepartment of Epidemiology and Public Health, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Jun HataCentre for Cohort Studies, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Shigeyuki NakajiDepartment of Social Medicine, Graduate School of Medicine, Hirosaki University, Hirosaki, Japan.
Tetsuya MaedaDivision of Neurology and Gerontology, Department of Internal Medicine, School of Medicine, Iwate Medical University, Iwate, Japan.
Kenjiro OnoDepartment of Neurology, Kanazawa University Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
Kenji NakashimaNational Hospital Organisation, Matsue Medical Centre, Matsue, Japan.
Jun-Ichi IgaDepartment of Neuropsychiatry, Molecules and Function, Ehime University Graduate School of Medicine, Matsuyama, Japan.ORCID https://orcid.org/0000-0003-4409-3096
Minoru TakebayashiFaculty of Life Sciences, Department of Neuropsychiatry, Kumamoto University, Kumamoto, Japan.
Toshiharu NinomiyaCentre for Cohort Studies, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Masaru MimuraDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
JPSC-AD Study Group

Funding

Japan Agency for Medical Research and Development
6 · The paper itself

Abstract

backgroundStudies have shown that decreased gait speed is associated with impaired cognitive function. However, whether this association is equivalent across ages or genders in the older population remains unclear. Thus, we examined the association between mild cognitive impairment (MCI) and gait speed emphasising the influence of age and gender.

methodsOverall, 8233 Japanese participants aged ≥65 years were enrolled in this cross-sectional study between 2016 and 2018. After stratification by gender and age group, the participants' gait speeds were divided into quintiles, and the difference in MCI prevalence at each gait speed quintile was calculated. Logistic regression analyses were performed to assess the odds of MCI for each quintile and to assess the influence of age and gender.

resultsMales had a consistently higher prevalence of MCI than females. The odds of MCI were increased as gait speed decreased. Logistic regression analyses revealed that in the multivariable-adjusted model 2, the odds ratios (95% confidence interval; CI) for MCI were 2.02 (1.47-2.76) for females and 1.75 (1.29-2.38) for males in the slowest gait speed quintiles compared to the fastest quintile. In the stratified analyses, only males showed an age-dependent increase in the associations between gait speed and MCI, while females exhibited comparable associations across age groups.

conclusionsReduced gait speed was associated with increased odds of MCI, and this association may vary according to gender and age. Therefore, gait speed could serve as a valuable screening tool for MCI, with gender- and age-dependent clinical implications.

Indexed as

Cognitive DysfunctionDementiaAgedAgingCross-Sectional StudiesEast Asian PeopleFemaleGaitHumansIndependent LivingJapanMaleProspective StudiesWalking Speedcross-sectional studygait speedmild cognitive impairment

Identifiers

PMID37533229
PMCPMC11578030

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.