Evidence map›Paper›PMID 37533213›Full record

ArticleFEMS microbiology reviews2023

Illuminating the oral microbiome: cellular microbiology.

Richard J Lamont, Daniel P Miller, Juhi Bagaitkar

Open access · bronzeAbstract read
In one paragraph

Article in FEMS microbiology reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Engineered Tissue Models to Decode Host-Microbiota Interactions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  11. Review
  12. Frontiers in cell and developmental biology · 2025
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Richard J LamontDepartment of Oral Immunology and Infectious Diseases, University of Louisville, Louisville, KY, KY40202, United States.ORCID 0000-0002-3147-5039
Daniel P MillerDepartment of Microbiology and Immunology, Virginia Commonwealth University, Richmond, VA, VA23298, United States.
Juhi BagaitkarCenter for Microbial Pathogenesis, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, OH43205, United States.
Nationwide Children's Hospital · USUniversity of Louisville · USVirginia Commonwealth University · US

Funding

MOLECULAR ASPECTS OF ORAL PLAQUE FORMATIONR01DE012505 · NIDCR · UNIVERSITY OF WASHINGTON · PI Richard J Lamont, JAN S POTEMPA · 1998 to 2026
$9.5M
P GINGIVALIS INTERACTIONS WITH GINGIVAL EPITHELIAL CELLSR01DE011111 · NIDCR · UNIVERSITY OF WASHINGTON · PI HARIBABU BODDULURI, Richard J Lamont · 1995 to 2026
$5.4M
Probing Polymicrobial Synergy Using hihg Throughout GenomicsR01DE023193 · NIDCR · UNIVERSITY OF TEXAS AT AUSTIN · PI LAMONT, RICHARD J, WHITELEY, MARVIN · 2013 to 2023
$4.7M
P.gingivalis Interactions with Gingival Epithelial CellsR37DE011111 · NIDCR · UNIVERSITY OF LOUISVILLE · PI LAMONT, RICHARD J · 2009 to 2018
$3.6M
Redox Regulation of Gingival InflammationR01DE028296 · NIDCR · UNIVERSITY OF LOUISVILLE · PI BAGAITKAR, JUHI · 2020 to 2024
$2.3M
Regulation and Manipulation of Oral Type III Interferon Responses by Porphyromonas gingivalisR01DE031756 · NIDCR · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI Juhi Bagaitkar, Richard J Lamont · 2023 to 2026
$1.7M
Polymicrobial Synergy between Treponema denticola and Porphyromonas gingivalisR00DE028346 · NIDCR · VIRGINIA COMMONWEALTH UNIVERSITY · PI MILLER, DANIEL PATRICK · 2020 to 2022
$747k
Polymicrobial Synergy between Treponema denticola and Porphyromonas gingivalisK99DE028346 · NIDCR · UNIVERSITY OF LOUISVILLE · PI MILLER, DANIEL PATRICK · 2018 to 2019
$214k
NIDCR NIH HHS K99 DE028346NIDCR NIH HHS R00 DE028346NIDCR NIH HHS R01 DE011111NIDCR NIH HHS R01 DE012505NIDCR NIH HHS R01 DE023193NIDCR NIH HHS R01 DE028296NIDCR NIH HHS R01 DE031756NIDCR NIH HHS R37 DE011111
6 · The paper itself

Abstract

Epithelial cells line mucosal surfaces such as in the gingival crevice and provide a barrier to the ingress of colonizing microorganisms. However, epithelial cells are more than a passive barrier to microbial intrusion, and rather constitute an interactive interface with colonizing organisms which senses the composition of the microbiome and communicates this information to the underlying cells of the innate immune system. Microorganisms, for their part, have devised means to manipulate host cell signal transduction pathways to favor their colonization and survival. Study of this field, which has become known as cellular microbiology, has revealed much about epithelial cell physiology, bacterial colonization and pathogenic strategies, and innate host responses.

Indexed as

MicrobiotaEpithelial CellsImmunity, InnateSignal Transductionepitheliuminvasionoralperiodontal, OSCCsignal transduction

Identifiers

PMID37533213
PMCPMC10657920
OpenAlexW4385514031

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.