Evidence map›Paper›PMID 37533126›Full record

ArticleKnee surgery & related research2023

Total knee arthroplasty in dialysis patients: a national in-patient sample-based study of perioperative complications.

Nikit Venishetty, Dane K Wukich, Jack Beale, J Riley Martinez, Michel Toutoungy, Varatharaj Mounasamy, Senthil Sambandam

Open access · diamondAbstract read
In one paragraph

Article in Knee surgery & related research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Increased Risk of Complications and Mortality After Total Joint Arthroplasty in Dialysis-Dependent Patients.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Nikit VenishettyPaul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, TX, USA. nikit.venishetty@ttuhsc.edu.ORCID http://orcid.org/0000-0002-2289-3079
Dane K WukichDepartment of Orthopedics, University of Texas Southwestern, Dallas VAMC, Dallas, TX, USA.
Jack BealeDepartment of Orthopedics, University of Texas Southwestern, Dallas VAMC, Dallas, TX, USA.
J Riley MartinezDepartment of Orthopedics, University of Texas Southwestern, Dallas VAMC, Dallas, TX, USA.
Michel ToutoungyPaul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, TX, USA.
Varatharaj MounasamyDepartment of Orthopedics, University of Texas Southwestern, Dallas VAMC, Dallas, TX, USA.
Senthil SambandamDepartment of Orthopedics, University of Texas Southwestern, Dallas VAMC, Dallas, TX, USA.
Dallas VA Medical Center · USTexas Tech University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) is a growing disease that affects millions of people in the USA every year. Many CKD patients progress to end-stage renal disease (ESRD), necessitating the use of hemodialysis to alleviate symptoms and manage kidney function. Furthermore, many of these patients have lower bone quality and experience more postoperative complications. However, there is currently limited information on hospitalization information and perioperative complications in this population following procedures such as total knee arthroplasty (TKA). The purpose of this study was to assess the patient characteristics, demographics, and prevalence of postoperative problems among dialysis patients who received TKA.

methodsIn this retrospective study, we used the Nationwide Inpatient Sample (NIS) data from 2016 to 2019 to analyze the incidence of perioperative complications, length of stay (LOS), and the cost of care (COC) among patients undergoing TKA who were categorized as dialysis patients, compared with those who were not. Propensity matching was conducted to consider associated factors that may influence perioperative complications.

resultsFrom 2016 to 2019, 558,371 patients underwent TKAs, according to the National In-Sample (NIS) database. Of those, 418 patients (0.1%) were in the dialysis group, while the remaining 557,953 patients were included in the control group. The mean age of the dialysis group was 65.4 ± 9.8 years, and the mean age in the control group was 66.7 ± 9.5 years (p = 0.006). After propensity matching, dialysis group patients had a higher risk of receiving blood transfusions [odds ratio (OR): 2; 95% confidence interval (CI): 1.2, 3.4] and a significantly larger COC in comparison to those in the control group (91,434.3 USD versus 71,943.6 USD, p < 0.001). In addition, dialysis patients had significantly higher discharges to another facility, as compared with the control group patients.

conclusionsThe dialysis group had a significantly higher cost of care, higher rates of requiring blood transfusion, and more cases of being discharged to another facility than non-dialysis patients. This data will help providers make informed decisions about patient care and resource allocation for dialysis patients undergoing TKA.

Indexed as

Chronic kidney diseaseCost of careDialysisLength of stayPostoperative complicationsTotal knee arthroplasty

Identifiers

PMID37533126
PMCPMC10394770
OpenAlexW4385492925

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.