ArticleJournal of neuroengineering and rehabilitation2023
Intracortical and intercortical networks in patients after stroke: a concurrent TMS-EEG study.
Article in Journal of neuroengineering and rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review: Resting state functional MRI as a biomarker for non-invasive brain stimulation in upper limb recovery post-stroke.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- Exploring Neurobiological Effects of Intermittent Theta-Burst Stimulation on the Left Cerebellum for Post-stroke Unilateral Neglect: A Preliminary Transcranial Magnetic Stimulation-Electroencephalography Investigation.Cerebellum (London, England) · 2025Trial
- Frequency-specific modulation of motor cortical excitability by transcranial alternating current stimulation.Journal of neuroengineering and rehabilitation · 2025Trial
- Functional near-infrared spectroscopy: Systematic mapping of abnormal brain function features in neurological disorders.Neural regeneration research · 2026Article
- Neurophysiological Predictors of Proximal Motor Rehabilitation in Stroke Patients with Corticospinal Tract Damage.Brain sciences · 2026Article
- Clinical utility and prospective of TMS-EEG: Updated review from an international expert group.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2026Review
- Mechanisms of acupuncture-regulated cortical plasticity after stroke based on TMS-EEG-MEP integration.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Age related alteration in EEG evoked responses to balance perturbations on an inclined surface.Scientific reports · 2026Article
- Brain Oscillatory Modes as a Proxy of Stroke Recovery.Neurorehabilitation and neural repair · 2025Article
- Reliable and efficient transcranial magnetic stimulation-electroencephalography (TMS-EEG) using ultra-thin active electrodes.Communications engineering · 2025Article
- The impact of high-frequency rTMS treatment on brain activity in PSCI patients: a TMS-EEG study.Frontiers in neurology · 2025Article
- Utilization of Single-Pulse Transcranial-Evoked Potentials in Neurological and Psychiatric Clinical Practice: A Narrative Review.Neurology international · 2024Review
- Facilitating Corticomotor Excitability of the Contralesional Hemisphere Using Non-Invasive Brain Stimulation to Improve Upper Limb Motor Recovery from Stroke-A Scoping Review.Journal of clinical medicine · 2024Article
- Cortico-cortical paired associative stimulation: a novel neurostimulation solution for modulating brain connectivity and networks.Frontiers in neuroscience · 2023Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundConcurrent transcranial magnetic stimulation and electroencephalography (TMS-EEG) recording provides information on both intracortical reorganization and networking, and that information could yield new insights into post-stroke neuroplasticity. However, a comprehensive investigation using both concurrent TMS-EEG and motor-evoked potential-based outcomes has not been carried out in patients with chronic stroke. Therefore, this study sought to investigate the intracortical and network neurophysiological features of patients with chronic stroke, using concurrent TMS-EEG and motor-evoked potential-based outcomes.
methodsA battery of motor-evoked potential-based measures and concurrent TMS-EEG recording were performed in 23 patients with chronic stroke and 21 age-matched healthy controls.
resultsThe ipsilesional primary motor cortex (M1) of the patients with stroke showed significantly higher resting motor threshold (P = 0.002), reduced active motor-evoked potential amplitudes (P = 0.001) and a prolonged cortical silent period (P = 0.007), compared with their contralesional M1. The ipsilesional stimulation also produced a reduction in N100 amplitude of TMS-evoked potentials around the stimulated M1 (P = 0.007), which was significantly correlated with the ipsilesional resting motor threshold (P = 0.011) and motor-evoked potential amplitudes (P = 0.020). In addition, TMS-related oscillatory power was significantly reduced over the ipsilesional midline-prefrontal and parietal regions. Both intra/interhemispheric connectivity and network measures in the theta band were significantly reduced in the ipsilesional hemisphere compared with those in the contralesional hemisphere.
conclusionsThe ipsilesional M1 demonstrated impaired GABA-B receptor-mediated intracortical inhibition characterized by reduced duration, but reduced magnitude. The N100 of TMS-evoked potentials appears to be a useful biomarker of post-stroke recovery.
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