Evidence map›Paper›PMID 37533004›Full record

ArticleBMC cardiovascular disorders2023

Machine learning-based models for predicting mortality and acute kidney injury in critical pulmonary embolism.

Geng Wang, Jiatang Xu, Xixia Lin, Weijie Lai, Lin Lv, Senyi Peng, Kechen Li, Mingli Luo, Jiale Chen, Dongxi Zhu and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMC cardiovascular disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Geng Wang *Department of Vascular Interventional Radiology, Zhongshan Hospital of Traditional Chinese Medicine, Zhongshan, China.
Jiatang Xu *Department of Cardiovascular Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No.33, Yingfeng Road, Haizhu District, Guangdong Province, 510000, Guangzhou, China.
Xixia Lin *Department of Medicine, Sun Yat-Sen Memorial Hospital South Campus Clinic, Guangzhou, China.
Weijie Lai *Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Lin LvZhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Senyi PengZhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Kechen LiHospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University, Guangzhou, China.
Mingli LuoZhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Jiale ChenZhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Dongxi ZhuZhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Xiong ChenDepartment of Urology, SunYat-Sen Memorial Hospital, SunYat-Sen University, Guangzhou, China.
Chen YaoDepartment of Vascular Surgery, First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Shaoxu WuDepartment of Urology, SunYat-Sen Memorial Hospital, SunYat-Sen University, Guangzhou, China. wushx29@mail.sysu.edu.cn.
Kai HuangDepartment of Cardiovascular Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No.33, Yingfeng Road, Haizhu District, Guangdong Province, 510000, Guangzhou, China. huangk37@mail.sysu.edu.cn.
Sun Yat-sen University · CNSun Yat-sen Memorial Hospital · CNJinan University · CNStomatology Hospital · CNThe First Affiliated Hospital, Sun Yat-sen University · CNZhongshan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe aimed to use machine learning (ML) algorithms to risk stratify the prognosis of critical pulmonary embolism (PE). MATERIAL AND

methodsIn total, 1229 patients were obtained from MIMIC-IV database. Main outcomes were set as all-cause mortality within 30 days. Logistic regression (LR) and simplified eXtreme gradient boosting (XGBoost) were applied for model constructions. We chose the final models based on their matching degree with data. To simplify the model and increase its usefulness, finally simplified models were built based on the most important 8 variables. Discrimination and calibration were exploited to evaluate the prediction ability. We stratified the risk groups based on risk estimate deciles.

resultsThe simplified XGB model performed better in model discrimination, which AUC were 0.82 (95% CI: 0.78-0.87) in the validation cohort, compared with the AUC of simplified LR model (0.75 [95% CI: 0.69-0.80]). And XGB performed better than sPESI in the validation cohort. A new risk-classification based on XGB could accurately predict low-risk of mortality, and had high consistency with acknowledged risk scores.

conclusionsML models can accurately predict the 30-day mortality of critical PE patients, which could further be used to reduce the burden of ICU stay, decrease the mortality and improve the quality of life for critical PE patients.

Indexed as

Acute Kidney InjuryPulmonary EmbolismHumansMachine LearningQuality of LifeRisk AssessmentIntensive care unitMachine learning (ML)MortalityPrognosisPulmonary embolism (PE)

Identifiers

PMID37533004
PMCPMC10399014
OpenAlexW4385492602

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.