Evidence map›Paper›PMID 37532692›Full record

ArticleCell death & disease2023

Single-cell profiling reveals the trajectory of FOLR2-expressing tumor-associated macrophages to regulatory T cells in the progression of lung adenocarcinoma.

Chan Xiang, Min Zhang, Zhanxian Shang, Shengnan Chen, Jikai Zhao, Bowen Ding, Dong Jiang, Qian Zhu, Haohua Teng, Lei Zhu and 5 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Single-cell dissection of pleural and systemic immunity uncovers pathogen-specific immune reprogramming in tuberculosis versus lung adenocarcinoma.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Immune activation induced by FOLR2Frontiers in immunology · 2026
    Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Observational
  20. FOLR2Cell communication and signaling : CCS · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Chan Xiang *Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.
Min Zhang *Novogene Co., Ltd., Beijing, 100015, China.ORCID http://orcid.org/0009-0007-4363-8492
Zhanxian Shang *Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.
Shengnan ChenDepartment of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.
Jikai ZhaoDepartment of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.
Bowen DingDepartment of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.
Dong JiangNovogene Co., Ltd., Beijing, 100015, China.
Qian ZhuDepartment of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.
Haohua TengDepartment of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.
Lei ZhuDepartment of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.
Jinchen ShaoDepartment of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.
Ruiying ZhaoDepartment of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.
Min YeDepartment of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China.
Yang YuNovogene Co., Ltd., Beijing, 100015, China. yuyang@novogene.com.ORCID http://orcid.org/0000-0002-4145-3642
Yuchen HanDepartment of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, China. ychan@cmu.edu.cn.ORCID http://orcid.org/0000-0002-2548-5492
Shanghai Jiao Tong University · CNNovogene Bioinformatics Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An immunosuppressive microenvironment enriched with regulatory CD4

Indexed as

AdenocarcinomaAdenocarcinoma of LungFolate Receptor 2Lung NeoplasmsChemokinesForkhead Transcription FactorsHumansLigandsT-Lymphocytes, RegulatoryTumor-Associated MacrophagesTumor MicroenvironmentChemokinesFolate Receptor 2FOLR2 protein, humanForkhead Transcription FactorsLigands

Identifiers

PMID37532692
PMCPMC10397223
OpenAlexW4385480859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.