Evidence map›Paper›PMID 37532549›Full record

ReviewInternal medicine (Tokyo, Japan)2024

Immune Checkpoint Inhibitor-induced Pancreatitis with Pancreatic Enlargement Mimicking Autoimmune Pancreatitis: A Case Report and Review of the Literature.

Kiyokuni Tanabe, Kensuke Yokoyama, Atsushi Kanno, Eriko Ikeda, Kozue Ando, Hiroki Nagai, Takahiro Koyanagi, Mio Sakaguchi, Takeo Nakaya, Kiichi Tamada and 4 more

Open access · diamondAbstract readReviewCase Reports
In one paragraph

Review in Internal medicine (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Autoimmune Pancreatitis: A Review.Journal of clinical medicine · 2025
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Kiyokuni TanabeDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Japan.
Kensuke YokoyamaDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Japan.
Atsushi KannoDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Japan.
Eriko IkedaDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Japan.
Kozue AndoDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Japan.
Hiroki NagaiDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Japan.
Takahiro KoyanagiDepartment of Obstetrics & Gynecology, Jichi Medical University, Japan.
Mio SakaguchiDepartment of Diagnostic Pathology, Jichi Medical University, Japan.
Takeo NakayaDepartment of Diagnostic Pathology, Jichi Medical University, Japan.
Kiichi TamadaDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Japan.
Toshiro NikiDepartment of Diagnostic Pathology, Jichi Medical University, Japan.
Noriyoshi FukushimaDepartment of Diagnostic Pathology, Jichi Medical University, Japan.
Alan Kawarai LeforDepartment of Surgery, Jichi Medical University, Japan.
Hironori YamamotoDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Japan.
Jichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 61-year-old woman was administered 35 cycles of pembrolizumab for the treatment of recurrent endometrial cancer, achieving a complete response. She presented with asymptomatic pancreatic enlargement and elevated hepatobiliary enzymes, but amylase and lipase levels were within the normal ranges. Intrapancreatic bile duct stenosis due to pancreatic enlargement was present, mimicking autoimmune pancreatitis on computed tomography performed before the onset of clinical manifestations. A histological examination of a biopsy specimen showed lymphocyte and plasma cell infiltration with dense fibrosis in the stroma. The patient was successfully treated with oral prednisolone. There were no manifestations of recurrent pancreatitis after tapering the prednisolone dose.

Indexed as

Autoimmune DiseasesAutoimmune PancreatitisPancreatitisFemaleHumansHypertrophyImmune Checkpoint InhibitorsMiddle AgedNeoplasm Recurrence, LocalPrednisoloneImmune Checkpoint InhibitorsPrednisoloneautoimmune pancreatitisICI-induced pancreatitisimmune checkpoint inhibitorspancreatitispembrolizumab

Identifiers

PMID37532549
PMCPMC11008994
OpenAlexW4385449927

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.