ReviewJournal of the American College of Cardiology2023
Bridging Treatment Implementation Gaps in Patients With Heart Failure: JACC Focus Seminar 2/3.
Review in Journal of the American College of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Digital consults in heart failure care: a randomized controlled trial.Nature medicine · 2024Trial
- Clinical Impact of Digital Health Interventions with Educational Components for Patients with Heart Failure: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2026Review
- A knowledge graph-driven paradigm for holistic symptom management: development and evaluation of a nurse-led KG-QA system in community palliative care.BMC palliative care · 2026Article
- Barriers and Facilitators to Heart Failure Guideline-Directed Medical Therapy in an Integrated Health System and Federally Qualified Health Centers: A Thematic Qualitative Analysis.Journal of general internal medicine · 2026Article
- SGLT2 Inhibitors in Heart Failure with Reduced Ejection Fraction: A Retrospective Cohort Analysis of Sex - Specific Cardiovascular Outcomes.Current cardiology reviews · 2026Article
- Review
- Identifying and overcoming barriers to referral in advanced heart failure. A scientific statement of the Heart Failure Association (HFA) of the ESC.European journal of heart failure · 2025Review
- Incorporating Implementation Science Into Frailty Interventions for Cardiovascular Disease.JACC. Advances · 2025Review
- Great debate: artificial intelligence will replace much of what cardiologists do.European heart journal · 2025Article
- No death gap, but a care gap: Rethinking gender and heart failure in India and the Philippines.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Advancement of the implementation of evidence-based therapies for cardiovascular-kidney-metabolic conditions: A multi-stakeholder perspective.American heart journal · 2025Review
- Electronic health record nudges to optimize guideline-directed medical therapy for heart failure.Heart failure reviews · 2025Review
- Review
- The application of neighborhood area deprivation index to improve health equity across the spectrum of heart failure: a review.Heart failure reviews · 2025Review
- Clinical Profile of Heart Failure Patients and Evaluation of the Prescribing Practice of Guideline Directed Medical Therapy (GDMT) at Rwanda Military Referral and Teaching Hospital: A Retrospective Study.International journal of general medicine · 2025Article
- Review
- Gamification and its Potential for Better Engagement in the Management of Heart Failure or Quality of Care Registries: A Viewpoint.Current heart failure reports · 2024Review
- A Guide to Implementation Science for Phase 3 Clinical Trialists: Designing Trials for Evidence Uptake.Journal of the American College of Cardiology · 2024Review
- Consistency of HFrEF treatment effect in underrepresented groups in randomized clinical trials.NPJ cardiovascular health · 2024Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Heart failure (HF) is a leading cause of death and disability in older adults. Despite decades of high-quality evidence to support their use, guideline-directed medical therapies (GDMTs) that reduce death and disease burden in HF have been suboptimally implemented. Approaches to closing care gaps have focused largely on strategies proven to be ineffective, whilst effective interventions shown to improve GDMT uptake have not been instituted. This review synthesizes implementation interventions that increase the uptake of GDMT, discusses barriers and facilitators of implementation, summarizes conceptual frameworks in implementation science that could improve knowledge uptake, and offers suggestions for trial design that could better facilitate end-of-trial implementation. We propose an evidence-to-care conceptual model that could foster the simultaneous generation of evidence and long-term implementation. By adopting principles of implementation science, policymakers, researchers, and clinicians can help reduce the burden of HF on patients and health care systems worldwide.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.