Evidence map›Paper›PMID 37532133›Full record

ArticleActa biomaterialia2023

Contribution of αβ T cells to macrophage polarization and MSC recruitment and proliferation on titanium implants.

Derek Avery, Lais Morandini, Melissa Gabriec, Luke Sheakley, Matthieu Peralta, Henry J Donahue, Rebecca K Martin, Rene Olivares-Navarrete

Open access · greenAbstract read
In one paragraph

Article in Acta biomaterialia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Advances on T cell immunity in bone remodeling and bone regeneration.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2024
    Review
  9. Review
  10. CD4Acta biomaterialia · 2024
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Derek AveryDepartment of Biomedical Engineering, College of Engineering, Virginia Commonwealth University, Richmond, VA, United States.
Lais MorandiniDepartment of Biomedical Engineering, College of Engineering, Virginia Commonwealth University, Richmond, VA, United States.
Melissa GabriecDepartment of Biomedical Engineering, College of Engineering, Virginia Commonwealth University, Richmond, VA, United States.
Luke SheakleyDepartment of Biomedical Engineering, College of Engineering, Virginia Commonwealth University, Richmond, VA, United States.
Matthieu PeraltaDepartment of Biomedical Engineering, College of Engineering, Virginia Commonwealth University, Richmond, VA, United States.
Henry J DonahueDepartment of Biomedical Engineering, College of Engineering, Virginia Commonwealth University, Richmond, VA, United States.
Rebecca K MartinDepartment of Microbiology and Immunology, School of Medicine, Virginia Commonwealth University, Richmond, VA, United States.
Rene Olivares-NavarreteDepartment of Biomedical Engineering, College of Engineering, Virginia Commonwealth University, Richmond, VA, United States. Electronic address: ronavarrete@vcu.edu.
Virginia Commonwealth University · US

Funding

Virus Vector Shared ResourceP30CA016059 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Renato Martins · 1985 to 2026
$51.0M
Role of Wnt Signaling in Macrophage Response to BiomaterialsR01DE028919 · NIDCR · VIRGINIA COMMONWEALTH UNIVERSITY · PI OLIVARES-NAVARRETE, RENE · 2019 to 2023
$1.8M
NCI NIH HHS P30 CA016059NIDCR NIH HHS R01 DE028919
6 · The paper itself

Abstract

Physiochemical cues like topography and wettability can impact the inflammatory response and tissue integration after biomaterial implantation. T cells are essential for immunomodulation of innate immune cells and play an important role in the host response to biomaterial implantation. This study aimed to understand how CD4

Indexed as

Mesenchymal Stem CellsTitaniumAnimalsBiocompatible MaterialsCell ProliferationMacrophagesMiceT-LymphocytesBiocompatible MaterialsTitaniumCD4CD8MacrophagesSurface modificationsTitaniumαβ T cells

Identifiers

PMID37532133
PMCPMC10528595
OpenAlexW4385407670

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.