ArticleAnnals of biomedical engineering2023
Survivability of Titanium Implant Materials: In Vitro Simulated Inflammatory and Infectious Environment.
Article in Annals of biomedical engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Functional design of anastomotic staples in gastrointestinal surgery: mechanistic insights and clinical translation.Biomedical engineering online · 2026Review
- Evaluating the potential hepatotoxicity from hip implant wear products-AnBiomaterials and biosystems · 2025Article
- Harnessing extracellular vesicles-mediated signaling for enhanced bone regeneration: novel insights into scaffold design.Biomedical materials (Bristol, England) · 2024Article
- GPT4: The Indispensable Helper for Neurosurgeons in the New Era.Annals of biomedical engineering · 2023Article
- Can ChatGPT be Trusted for Consulting? Uncovering Doctor's Perceptions Using Deep Learning Techniques.Annals of biomedical engineering · 2023Article
- Can ChatGPT be Trusted for Consulting? Uncovering Doctor's Perceptions Using Deep Learning Techniques.Annals of biomedical engineering · 2023Article
- AI Tackles Pandemics: ChatGPT's Game-Changing Impact on Infectious Disease Control.Annals of biomedical engineering · 2023Article
- GPT4: The Indispensable Helper for Neurosurgeons in the New Era.Annals of biomedical engineering · 2023Article
- Artificial Intelligence in Intensive Care Medicine: Toward a ChatGPT/GPT-4 Way?Annals of biomedical engineering · 2023Article
- Artificial Intelligence in Intensive Care Medicine: Toward a ChatGPT/GPT-4 Way?Annals of biomedical engineering · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Titanium-based implants utilized in total joint arthroplasties could restore primary musculoskeletal function to patients suffering from osteoarthritis and other conditions. Implants are susceptible to failure stemming from aseptic loosening and infection at the joint site, eventually requiring revision surgery. We hypothesized that there might be a feedback loop by which metal degradation particles and ions released from the implant decrease cell viability and increase immune response, thereby creating biochemical conditions that increase the corrosion rate and release more metal ions. This study focused on the synergistic process through cell viability assays and electrochemical tests. From the results, inflammatory conditions from ion release resulting in cell death would further increase the corrosion rate at the metal implant site. The synergistic interaction in the implant surroundings in which infectious conditions produce Ti ions that contribute to more infection, creating a potential cycle of accelerating corrosion.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.