Evidence map›Paper›PMID 37530791›Full record

ReviewVirchows Archiv : an international journal of pathology2023

Mediastinal large B cell lymphoma and surrounding gray areas: a report of the lymphoma workshop of the 20th meeting of the European Association for Haematopathology.

Sarah E Gibson, Stefan Dojcinov, Snjezana Dotlic, Sylvia Hartmann, Eric D Hsi, Monika Klimkowska, Federica Melle, Stefano A Pileri, Colleen A Ramsower, Karen Rech and 5 more

Open access · hybridAbstract readReview
In one paragraph

Review in Virchows Archiv : an international journal of pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 12 institutions in 9 countries.

Sarah E GibsonDivision of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, AZ, USA.ORCID http://orcid.org/0000-0003-2427-6442
Stefan DojcinovDepartment of Pathology, Morriston Hospital, Swansea Bay University Health Board, Swansea, UK.
Snjezana DotlicDepartment of Pathology and Cytology, University Hospital Centre Zagreb, Zagreb, Croatia.ORCID http://orcid.org/0000-0002-2036-9206
Sylvia HartmannDr. Senckenberg Institute of Pathology, Goethe University Frankfurt Am Main, Frankfurt Am Main, Germany.ORCID http://orcid.org/0000-0003-3424-1091
Eric D HsiDepartment of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Monika KlimkowskaDepartment of Clinical Pathology and Cancer Diagnostics, Karolinska University Hospital, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-3391-930X
Federica MelleDivision of Haematopathology, IEO, European Institute of Oncology IRCCS, Milan, Italy.ORCID http://orcid.org/0000-0001-8032-5128
Stefano A PileriDivision of Haematopathology, IEO, European Institute of Oncology IRCCS, Milan, Italy.
Colleen A RamsowerDepartment of Research, Mayo Clinic, Scottsdale, AZ, USA.ORCID http://orcid.org/0000-0002-4991-7712
Karen RechDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0001-6770-2339
Lisa M RimszaDivision of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, AZ, USA.ORCID http://orcid.org/0000-0003-1268-2750
Socorro Maria Rodriguez-PinillaPathology Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.ORCID http://orcid.org/0000-0002-2191-1327
Thomas A TousseynDepartment of Imaging and Pathology, Translational Cell and Tissue Research Lab, KU Leuven, Louvain, Belgium.ORCID http://orcid.org/0000-0002-0397-1086
Daphne de JongDepartment of Pathology, Amsterdam UMC, Location VUMC, De Boelelaan 1117, 1081HV, Amsterdam, The Netherlands. d.dejong2@amsterdamumc.nl.ORCID http://orcid.org/0000-0002-9725-4060
Elena SabattiniHaematopathology Unit, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy.ORCID http://orcid.org/0000-0002-4136-3591
Istituti di Ricovero e Cura a Carattere Scientifico · ITMayo Clinic Hospital · USMayo Clinic in Arizona · USAmsterdam Neuroscience · NLAzienda USL di Bologna · ITGoethe University Frankfurt · DEHospital Universitario Fundación Jiménez Díaz · ESKarolinska University Hospital · SEKU Leuven · BESwansea Bay University Health Board · GBUniversity Hospital Centre Zagreb · HRWake Forest University · US

Funding

Associazione Italiana per la Ricerca sul Cancro 5‰ n.21198
6 · The paper itself

Abstract

Session 3 of the 2021 European Association for Haematopathology/Society for Hematopathology Workshop focused on mediastinal large B cell lymphomas and surrounding gray areas. One half of the session was dedicated to primary mediastinal large B cell lymphoma (PMBL) and included cases with classic clinicopathologic features, as well as cases with either morphologic or immunophenotypic variation, and PMBL-like cases with primary extramediastinal disease. The role of additional immunophenotyping and/or molecular testing to aid in the diagnosis of PMBL was discussed. The second half of the session focused on mediastinal and non-mediastinal gray zone lymphomas (GZL) with features intermediate between diffuse large B cell lymphoma (DLBCL) and classic Hodgkin lymphoma (CHL). Several cases illustrating the current challenges in separating this entity from PMBL/DLBCL and CHL were presented. There was discussion regarding the clinical and genetic differences between mediastinal and non-mediastinal GZLs. Rare cases of PMBL and GZL associated with EBV or follicular lymphoma were reviewed. Finally, several cases included in the session highlighted composite or sequential CHL and PMBL/DLBCL and/or GZL, highlighting challenges in separating such cases from GZL.

Indexed as

Hodgkin DiseaseLymphoma, FollicularLymphoma, Large B-Cell, DiffuseMediastinal NeoplasmsBiomarkers, TumorHumansBiomarkers, TumorB cell lymphoma, Unclassifiable, with features intermediate between diffuse large B cell lymphoma and classic Hodgkin lymphomaClassic Hodgkin lymphomaComposite lymphomaGray zone lymphomaMediastinal gray zone lymphomaPrimary mediastinal large B cell lymphoma

Identifiers

PMID37530791
PMCPMC10700426
OpenAlexW4385477519

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.