Evidence map›Paper›PMID 37530672›Full record

ArticleInorganic chemistry2023

A Conformationally Restricted Gold(III) Complex Elicits Antiproliferative Activity in Cancer Cells.

Sailajah Gukathasan, Oluwatosin A Obisesan, Setareh Saryazdi, Libby Ratliff, Sean Parkin, Robert B Grossman, Samuel G Awuah

Open access · greenAbstract read
In one paragraph

Article in Inorganic chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sailajah GukathasanDepartment of Chemistry, University of Kentucky, Lexington, Kentucky 40506, United States.
Oluwatosin A ObisesanDepartment of Chemistry, University of Kentucky, Lexington, Kentucky 40506, United States.
Setareh SaryazdiDepartment of Chemistry, University of Kentucky, Lexington, Kentucky 40506, United States.
Libby RatliffDepartment of Chemistry, University of Kentucky, Lexington, Kentucky 40506, United States.ORCID 0000-0002-0187-9921
Sean ParkinDepartment of Chemistry, University of Kentucky, Lexington, Kentucky 40506, United States.
Robert B GrossmanDepartment of Chemistry, University of Kentucky, Lexington, Kentucky 40506, United States.ORCID 0000-0001-8866-3754
Samuel G AwuahDepartment of Chemistry, University of Kentucky, Lexington, Kentucky 40506, United States.ORCID 0000-0003-4947-7283
University of Kentucky · US

Funding

University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI Jennifer F Rogers · 2013 to 2026
$38.3M
Understanding the role of anti-apolipoprotein A-I antibodies in atherosclerotic cardiovascular diseaseP20GM130456 · NIGMS · UNIVERSITY OF KENTUCKY · PI Jon Scott Thorson · 2020 to 2026
$18.7M
Gold-derived Therapeutic Compounds for Disease ApplicationR01CA258421 · NCI · UNIVERSITY OF KENTUCKY · PI AWUAH, SAMUEL GORMAN · 2021 to 2025
$1.7M
NCI NIH HHS P30 CA177558NCI NIH HHS R01 CA258421NIGMS NIH HHS P20 GM130456
6 · The paper itself

Abstract

Diamine ligands are effective structural scaffolds for tuning the reactivity of transition-metal complexes for catalytic, materials, and phosphorescent applications and have been leveraged for biological use. In this work, we report the synthesis and characterization of a novel class of cyclometalated [C^N] Au(III) complexes bearing secondary diamines including a norbornane backbone, (2

Indexed as

Antineoplastic AgentsOvarian NeoplasmsCell Line, TumorCrystallography, X-RayDiaminesFemaleGoldHumansLigandsNorbornanesAntineoplastic AgentsDiaminesGoldLigandsNorbornanes

Identifiers

PMID37530672
PMCPMC11268950
OpenAlexW4385476671

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.