Evidence map›Paper›PMID 37530224›Full record

ArticleBrain pathology (Zurich, Switzerland)2024

MET fusions and splicing variants is a strong adverse prognostic factor in astrocytoma, isocitrate dehydrogenase mutant.

Lingyu Liu, Ke-Nan Zhang, Zheng Zhao, Guanzhang Li, Rui-Chao Chai, Zhuoqun Li, Xing Liu, Jing Chen, Tao Jiang

Abstract readLetter
In one paragraph

Article in Brain pathology (Zurich, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lingyu LiuDepartment of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Ke-Nan ZhangDepartment of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Zheng ZhaoDepartment of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Guanzhang LiDepartment of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Rui-Chao ChaiDepartment of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.ORCID 0000-0003-3451-8871
Zhuoqun LiDepartment of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Xing LiuDepartment of Neuropathology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Jing ChenDepartment of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Tao JiangDepartment of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.ORCID 0000-0002-7008-6351

Funding

Beijing Nova Program Z201100006820118National Natural Science Foundation of China 81902533National Natural Science Foundation of China 82002647National Natural Science Foundation of China 82103623National Natural Science Foundation of China 82192894National Natural Science Foundation of China 82202896National Natural Science Foundation of China 82272867The National Key Research and Development Program of China 2019YFE0109400Training Fund for Open Projects at Clinical Institutes and Departments of Capital Medical University CCMU2022ZKYXY001 Liuxing
6 · The paper itself

Abstract

Liu et al. describe the adverse prognostic role of MET fusions and splicing variants in astrocytoma, isocitrate dehydrogenase mutant. On this basis, MET fusions and splicing variants was suggested to be a biomarker for the diagnosis of high-grade astrocytoma, isocitrate dehydrogenase mutant.

Indexed as

AstrocytomaBrain NeoplasmsHumansIsocitrate DehydrogenaseMutationPrognosisIsocitrate Dehydrogenaseastrocytoma IDH mutantbiomarkerMET variationprognosticWHO CNS grading

Identifiers

PMID37530224
PMCPMC11007006

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.