Evidence map›Paper›PMID 37530134›Full record

ArticleRedox report : communications in free radical research2023

Reduction of butyric acid-producing bacteria in the ileal mucosa-associated microbiota is associated with the history of abdominal surgery in patients with Crohn's disease.

Osamu Handa, Hiroto Miura, Tingting Gu, Motoyasu Osawa, Hiroshi Matsumoto, Eiji Umegaki, Ryo Inoue, Yuji Naito, Akiko Shiotani

Open access · goldAbstract read
In one paragraph

Article in Redox report : communications in free radical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Osamu HandaDepartment of Gastroenterology and Hepatology, Kawasaki Medical School, Kurashiki, Okayama, Japan.ORCID 0000-0003-2228-0405
Hiroto MiuraFaculty of Agriculture, Setsunan University, Hirakata-city, Osaka, Japan.ORCID 0000-0003-1736-4428
Tingting GuDepartment of Gastroenterology and Hepatology, Kawasaki Medical School, Kurashiki, Okayama, Japan.ORCID 0009-0005-3040-0149
Motoyasu OsawaDepartment of Gastroenterology and Hepatology, Kawasaki Medical School, Kurashiki, Okayama, Japan.ORCID 0000-0001-8882-0086
Hiroshi MatsumotoDepartment of Gastroenterology and Hepatology, Kawasaki Medical School, Kurashiki, Okayama, Japan.ORCID 0000-0003-2810-2888
Eiji UmegakiDepartment of Gastroenterology and Hepatology, Kawasaki Medical School, Kurashiki, Okayama, Japan.ORCID 0000-0003-3724-2604
Ryo InoueFaculty of Agriculture, Setsunan University, Hirakata-city, Osaka, Japan.ORCID 0000-0002-7233-366X
Yuji NaitoDepartment of Human Immunology and Nutrition Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.ORCID 0000-0001-5443-788X
Akiko ShiotaniDepartment of Gastroenterology and Hepatology, Kawasaki Medical School, Kurashiki, Okayama, Japan.ORCID 0000-0002-0393-2642
Kawasaki Medical School · JPSetsunan University · JPKyoto Prefectural University of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fecal microbiota is a significant factor determining the cause, course, and prognosis of Crohn's disease (CD). However, the factors affecting mucosa-associated microbiota (MAM) remain unclear. This retrospective study examined the differences in ileal MAM between CD patients and healthy controls and investigated the factors affecting MAM in CD patients to clarify potential therapeutic targets. Ileal MAM was obtained using brush forceps during endoscopic examination from 23 healthy controls and 32 CD patients (most were in remission). The samples' microbiota was profiled using the Illumina MiSeq platform. Compared to controls, CD patients had significantly reduced

Indexed as

Crohn DiseaseGastrointestinal MicrobiomeMicrobiotaBacteriaButyric AcidHumansIleumIntestinal MucosaRetrospective StudiesButyric Acidabdominal surgerybutyric acid-producing bacteriaCrohn’s diseaseInflammatory bowel diseaseintestinal dysbiosismucosa-associated microbiotaoxygenterminal ileum

Identifiers

PMID37530134
PMCPMC10402863
OpenAlexW4385476430

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.