Evidence map›Paper›PMID 37529852›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2023

Complex urban atmosphere alters alveolar stem cells niche properties and drives lung fibrosis.

Randa Belgacemi, Bruno Ribeiro Baptista, Grégoire Justeau, Marylène Toigo, Andrew Frauenpreis, Rojda Yilmaz, Audrey Der Vartanian, Mathieu Cazaunau, Edouard Pangui, Antonin Bergé and 9 more

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Inhaled Pollutants of the Gero-Exposome and Later-Life Health.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 3 countries.

Randa BelgacemiUniversité Paris Est Créteil, INSERM, IMRB, FHU Senec, Créteil, France.ORCID 0000-0001-7884-3567
Bruno Ribeiro BaptistaUniversité Paris Est Créteil, INSERM, IMRB, FHU Senec, Créteil, France.
Grégoire JusteauUniversité Paris Est Créteil, INSERM, IMRB, FHU Senec, Créteil, France.
Marylène ToigoUniversité Paris Est Créteil, INSERM, IMRB, FHU Senec, Créteil, France.
Andrew FrauenpreisLundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center, Torrance, California, United States.
Rojda YilmazUniversité Paris Est Créteil, INSERM, IMRB, FHU Senec, Créteil, France.
Audrey Der VartanianUniversité Paris Est Créteil, INSERM, IMRB, FHU Senec, Créteil, France.ORCID 0000-0003-1998-2107
Mathieu CazaunauUniversité Paris Est Créteil and Université Paris Cité, CNRS, LISA, Créteil, France.
Edouard PanguiUniversité Paris Est Créteil and Université Paris Cité, CNRS, LISA, Créteil, France.
Antonin BergéUniversité Paris Cité and Université Paris Est Créteil, CNRS, LISA, Paris, France.
Aline GratienUniversité Paris Cité and Université Paris Est Créteil, CNRS, LISA, Paris, France.
Juan Camilo Macias RodriguezUniversité Paris Cité and Université Paris Est Créteil, CNRS, LISA, Paris, France.
Saverio BellusciGerman Center for Lung Research (DZL), Department of Pulmonary and Critical Care Medicine and Infectious Diseases, Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Justus Liebig University Giessen, Giessen, Germany.
Geneviève DerumeauxUniversité Paris Est Créteil, INSERM, IMRB, FHU Senec, Créteil, France.ORCID 0000-0003-1471-1631
Jorge BoczkowskiUniversité Paris Est Créteil, INSERM, IMRB, FHU Senec, Créteil, France.
Denise Al AlamLundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center, Torrance, California, United States.ORCID 0000-0003-3148-7352
Patrice CollUniversité Paris Cité and Université Paris Est Créteil, CNRS, LISA, Paris, France.
Sophie LanoneUniversité Paris Est Créteil, INSERM, IMRB, FHU Senec, Créteil, France.
Laurent BoyerUniversité Paris Est Créteil, INSERM, IMRB, FHU Senec, Créteil, France.ORCID 0000-0002-2608-6696
Inserm · FRCentre National de la Recherche Scientifique · FRUCLA Medical Center · USJustus-Liebig-Universität Gießen · DE

Funding

Mechanisms controlling early human lung developmentR01HL141856 · NHLBI · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI AL-ALAM, DENISE · 2018 to 2022
$2.5M
NHLBI NIH HHS R01 HL141856
6 · The paper itself

Abstract

There is growing evidence suggesting that urban pollution has adverse effects on lung health. However, how urban pollution affects alveolar mesenchymal and epithelial stem cell niches remains unknown. This study aimed to determine how complex representative urban atmospheres alter alveolar stem cell niche properties. Mice were placed in an innovative chamber realistically simulating the atmosphere of a megalopolis, or "clean air," for 7 days. Lungs were collected, and fibroblasts and epithelial cells (EpCAM

Indexed as

Pulmonary FibrosisAlveolar Epithelial CellsAnimalsCell DifferentiationCollagenEpithelial Cell Adhesion MoleculeLungMiceStem CellsCollagenEpithelial Cell Adhesion Moleculealveolar stem cell nichecomplex atmospherefibrosislungurban

Identifiers

PMID37529852
PMCPMC10639009
OpenAlexW4385476223

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.