Evidence map›Paper›PMID 37529707›Full record

ArticleIEEE sensors letters2023

Handheld ISFET Lab-on-Chip detection of TMPRSS2-ERG and AR mRNA for prostate cancer prognostics.

Joseph Broomfield, Melpomeni Kalofonou, Sylvia Franklin, Sue M Powell, Thomas Pataillot-Meakin, Nicolas Moser, Charlotte L Bevan, Pantelis Georgiou

Abstract read
In one paragraph

Article in IEEE sensors letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Long-term performance of low-cost free chlorine sensors to monitor on-site water reuse.Water science and technology : a journal of the International Association on Water Pollution Research · 2025
    Article
  2. Review
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joseph BroomfieldCentre for BioInspired Technology, Electrical and Electronic Engineering, Imperial College London, UK, SW7 2AZ.
Melpomeni KalofonouCentre for BioInspired Technology, Electrical and Electronic Engineering, Imperial College London, UK, SW7 2AZ.
Sylvia FranklinCentre for BioInspired Technology, Electrical and Electronic Engineering, Imperial College London, UK, SW7 2AZ.
Sue M PowellImperial Centre for Translational and Experimental Medicine, Department of Surgery and Cancer, Imperial College London, UK, W12 0NN.
Thomas Pataillot-MeakinImperial Centre for Translational and Experimental Medicine, Department of Surgery and Cancer, Imperial College London, UK, W12 0NN.
Nicolas MoserCentre for BioInspired Technology, Electrical and Electronic Engineering, Imperial College London, UK, SW7 2AZ.
Charlotte L BevanImperial Centre for Translational and Experimental Medicine, Department of Surgery and Cancer, Imperial College London, UK, W12 0NN.
Pantelis GeorgiouCentre for BioInspired Technology, Electrical and Electronic Engineering, Imperial College London, UK, SW7 2AZ.

Funding

EPA EP-D-18-001
6 · The paper itself

Abstract

Ion-sensitive field-effect transistors (ISFETs) in combination with unmodified complementary metal oxide semiconductors present a point-of-care platform for clinical diagnostics and prognostics. This work illustrates the sensitive and specific detection of two circulating mRNA markers for prostate cancer, the androgen receptor and the TMPRSS2-ERG fusion using a target-specific loop-mediated isothermal amplification method. TMPRSS2-ERG and androgen receptor RNA were detected down to 3x10

Indexed as

BiosensorsISFETsLab-on-ChipProstate cancerRNART-LAMP

Identifiers

PMID37529707
PMCPMC7614862

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.