Evidence map›Paper›PMID 37529611›Full record

ArticleFrontiers in endocrinology2023

GDF10 is related to obesity as an adipokine derived from subcutaneous adipose tissue.

Mi Kyung Song, Ji Eun Kim, Jung Tae Kim, Yea Eun Kang, Sun Jong Han, Seok Hwan Kim, Hyun Jin Kim, Bon Jeong Ku, Ju Hee Lee

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mi Kyung SongDepartment of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Ji Eun KimResearch Center for Endocrine and Metabolic Disease, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Jung Tae KimResearch Center for Endocrine and Metabolic Disease, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Yea Eun KangDepartment of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Sun Jong HanDepartment of General Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Seok Hwan KimDepartment of General Surgery, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Hyun Jin KimDepartment of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Bon Jeong KuDepartment of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Ju Hee LeeDepartment of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Adipokines are proteins that are secreted by the adipose tissue. Although they are associated with obesity-related metabolic disorders, most studies have focused on adipokines expressed by visceral adipose tissue (VAT). This study aimed to identify the adipokine potentially derived from subcutaneous adipose tissue (SAT) and its clinical significance. Methods: Samples of SAT and VAT were obtained from six adult male patients who underwent laparoscopic surgery for benign gall bladder disease. Differentially expressed genes were analyzed by subjecting the samples to RNA sequencing. The serum concentration of selected proteins according to body mass index (BMI) was analyzed in 58 individuals. Results: Conclusions:

Indexed as

AdipokinesObesityAdipose TissueAdultGrowth Differentiation Factor 10HumansInsulinMaleSubcutaneous FatAdipokinesGDF10 protein, humanGrowth Differentiation Factor 10Insulinadipokinesadipose tissueGDF10obesitysubcutaneous fat

Identifiers

PMID37529611
PMCPMC10390302

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.