ArticleAdvances in neural information processing systems2022
Amortized Inference for Heterogeneous Reconstruction in Cryo-EM.
Article in Advances in neural information processing systems, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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Who cites it
19 citing papers in PubMed.
- Expansion omics: from expansion microscopy to spatial omics.Molecular systems biology · 2026Review
- CryoEMNet driven symmetry-aware molecular reconstruction through deep learning enhanced electron microscopy.Scientific reports · 2025Article
- Unsupervised Identification of Protein Compositions and Conformations via Implicit Content-Transformation Disentanglement.Proceedings. IEEE International Conference on Computer Vision · 2025Article
- One-step nanoscale expansion microscopy reveals individual protein shapes.Nature biotechnology · 2025Article
- Super-resolution microscopy for structural biology.Nature methods · 2025Review
- Scalable 3D reconstruction for X-ray single particle imaging with online machine learning.Nature communications · 2025Article
- Efficient high-resolution refinement in cryo-EM with stochastic gradient descent.Acta crystallographica. Section D, Structural biology · 2025Article
- Article
- Amortized template matching of molecular conformations from cryoelectron microscopy images using simulation-based inference.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- InstaMap: instant-NGP for cryo-EM density maps.Acta crystallographica. Section D, Structural biology · 2025Article
- Cryo-EM heterogeneity analysis using regularized covariance estimation and kernel regression.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- High-resolution protein modeling through Cryo-EM and AI: current trends and future perspectives - a review.Frontiers in molecular biosciences · 2025Review
- Cryo-EM Heterogeneity Analysis using Regularized Covariance Estimation and Kernel Regression.bioRxiv : the preprint server for biology · 2024Article
- CryoTRANS: predicting high-resolution maps of rare conformations from self-supervised trajectories in cryo-EM.Communications biology · 2024Article
- MDSPACE and MDTOMO Software for Extracting Continuous Conformational Landscapes from Datasets of Single Particle Images and Subtomograms Based on Molecular Dynamics Simulations: Latest Developments in ContinuousFlex Software Package.International journal of molecular sciences · 2023Article
- Capturing dynamical correlations using implicit neural representations.Nature communications · 2023Article
- Novel Artificial Intelligence-Based Approaches for Ab Initio Structure Determination and Atomic Model Building for Cryo-Electron Microscopy.Micromachines · 2023Review
- Methods for Cryo-EM Single Particle Reconstruction of Macromolecules Having Continuous Heterogeneity.Journal of molecular biology · 2023Review
- Integrating Molecular Models Into CryoEM Heterogeneity Analysis Using Scalable High-resolution Deep Gaussian Mixture Models.Journal of molecular biology · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Cryo-electron microscopy (cryo-EM) is an imaging modality that provides unique insights into the dynamics of proteins and other building blocks of life. The algorithmic challenge of jointly estimating the poses, 3D structure, and conformational heterogeneity of a biomolecule from millions of noisy and randomly oriented 2D projections in a computationally efficient manner, however, remains unsolved. Our method, cryoFIRE, performs
Identifiers
37529401PMC10392957What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.