Evidence map›Paper›PMID 37529341›Full record

ArticleHeliyon2023

Identification of the relationship between single-cell N6-methyladenosine regulators and the infiltrating immune cells in esophageal carcinoma.

Yunyi Bian, Guoshu Bi, Guangyao Shan, Jiaqi Liang, Guangyu Yao, Qihai Sui, Zhengyang Hu, Cheng Zhan, Zhencong Chen, Qun Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yunyi BianDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Guoshu BiDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Guangyao ShanDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Jiaqi LiangDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Guangyu YaoDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Qihai SuiDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Zhengyang HuDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Cheng ZhanDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Zhencong ChenDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Qun WangDepartment of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: N6-methyladenosine (m Methods: The single-cell transcriptome data from five ESCC patients in our hospital were analyzed, and TME clusters associated with prognosis and immune checkpoint genes were investigated. Cell isolation and qPCR were conducted to validate the gene characterization in different cells. Results: According to distinct biological processes and marker genes, macrophages, T cells, and B cells clustered into three to four different subgroups. In addition, we demonstrated that m Conclusion: Overall, our study demonstrated for the first time the function of m

Indexed as

Cell communicationEsophageal squamous carcinomaN6-methyladenosineSingle-cellTumor microenvironment

Identifiers

PMID37529341
PMCPMC10388170

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.