Evidence map›Paper›PMID 37529315›Full record

ArticleFrontiers in psychology2023

Salivary testosterone and cortisol levels in borderline personality disorder before and after a 12-week group dialectical behavior therapy intervention.

Tori Dyson, Susan J Thomas, Michelle L Townsend, Adam Finch, Alexandra South, Emma Barkus, Emma Walter, Carley Mendonca, Brin F S Grenyer, Judy A Pickard

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in psychology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tori DysonSchool of Psychology, University of Wollongong, Wollongong, NSW, Australia.
Susan J ThomasSchool of Medicine, University of Wollongong, Wollongong, NSW, Australia.
Michelle L TownsendSchool of Psychology, University of Wollongong, Wollongong, NSW, Australia.
Adam FinchSchool of Psychology, University of Wollongong, Wollongong, NSW, Australia.
Alexandra SouthSchool of Psychology, University of Wollongong, Wollongong, NSW, Australia.
Emma BarkusDepartment of Psychology, Northumbria University, Newcastle upon Tyne, North East England, United Kingdom.
Emma WalterSchool of Psychology, Western Sydney University, Penrith, NSW, Australia.
Carley MendoncaSchool of Psychology, University of Technology Sydney, Sydney, NSW, Australia.
Brin F S GrenyerSchool of Psychology, University of Wollongong, Wollongong, NSW, Australia.
Judy A PickardSchool of Psychology, University of Wollongong, Wollongong, NSW, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Borderline Personality Disorder (BPD) is a chronic, debilitating, and difficult to treat condition. BPD has recently been linked to steroid hormone dysregulation and medical conditions characterized by disturbed androgen metabolism. This study aimed to investigate cortisol and testosterone levels in BPD, and changes in hormones following psychological treatment. Methods: Participants with BPD ( Results: Participants with BPD had significantly higher testosterone levels than controls. Mean testosterone levels in females with BPD were double that of female controls. Testosterone and cortisol levels were related, and some BPD symptoms were associated with with hormone levels. BPD symptoms reduced significantly with treatment, however pre to post hormone levels did not change. Conclusions: This study supports an association between BPD symptoms and neuroendocrine dysfunction at baseline, however we found no reduction in hormone dysfunction post treatment. Further research into relationships between stress signaling and neuroendocrine disturbances in BPD may inform aetiological and treatment models. Trial registration: Australian New Zealand Clinical Trials Registry ACTRN12618000477224. Registered on 3 April 2018.

Indexed as

borderline personality disorderhypothalamic-pituitary-adrenal axishypothalamic-pituitary-gonadal axissalivary cortisolsalivary testosterone

Identifiers

PMID37529315
PMCPMC10389657

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.