ReviewNeurology. Clinical practice2023
Risk Factors for External Ventricular Drainage-Related Infection: A Systematic Review and Meta-analysis.
Review in Neurology. Clinical practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Is there a way to reduce the infection associated with external ventricular shunts? A systematic review and meta-analysis of the recent bundle of care.Neurosurgical review · 2026Pooled it
- Impact of initial disease severity and metabolic stress on mortality in patients with suspected external ventricular drain-associated infection.Neurosurgical review · 2026Article
- Incidence, risk factors, and microbial spectrum of external ventricular drain-related infections among adult neurocritical care patients: A systematic review and meta-analysis.Journal of the Intensive Care Society · 2026Article
- Article
- Postoperative Neurocritical Care After Minimally Invasive Evacuation of Spontaneous Intracerebral Hemorrhage.Neurocritical care · 2026Review
- Handmade external ventricular drainage in resource-limited settings: safety, feasibility, and cost-effectiveness from a Peruvian cohort and global evidence review.Neurosurgical review · 2026Review
- Incidence and patient-related risk factors for external ventricular drain-related cerebrospinal fluid infections.Brain & spine · 2026Article
- A pragmatic evaluation of serum IL-6, PCT and CRP compared to routine CSF biomarkers and CDC/IDSA criteria in healthcare-associated Ventriculitis.Surgical neurology international · 2026Article
- Risk factors for nosocomial meningitis in patients with external ventricular drainages.Journal of intensive care · 2025Article
- CT ventriculographic identification and neuroendoscopic treatment of acquired hydrocephalus due to cerebral aqueduct lesions: a two-case report.Frontiers in oncology · 2025Article
- Development of an Evidence-based Care Bundle for Prevention of External Ventricular Drain-related Infection: Results of a Single-center Prospective Cohort Study and Literature Review.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- Infections Associated with Medtronic Duet External Ventricular Drains - Rhode Island Hospital, Providence, Rhode Island, January 2023-January 2024.MMWR. Morbidity and mortality weekly report · 2024Article
- Human platelet lysate: a potential therapeutic for intracerebral hemorrhage.Frontiers in neuroscience · 2024Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Objectives: External ventricular drainage (EVD) is one of the most commonly performed neurosurgical procedures, but EVD-related infection constitutes a significant health concern. Yet, little consensus identifies the risk factors for the development of EVD-related infection. Therefore, we performed a meta-analysis to systematically summarize existing evidence on the incidence and risk factors for EVD-related infection. Methods: PubMed, Embase, and the Cochrane Library databases from database inception to February 28, 2022, were searched for all studies investigating the incidence and risk factors for EVD-related infection. Data were assessed by R-4.2.0 software. The meta-analysis was used to calculate pooled odds ratios (OR) and 95% confidence intervals (CI). Results: A total of 48 studies were included. Among the 29 factors analyzed, statistically significant risk factors were subarachnoid hemorrhage(SAH)/intraventricular hemorrhage(IVH) (OR = 1.48, 95% CI = 1.20-1.82, Discussion: The meta-analysis of various relevant factors in the onset of EVD-related infection in patients submitted to EVD enabled us to establish a more probable profile of the patients who are more likely to develop it during the treatment.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.