Evidence map›Paper›PMID 37529259›Full record

ArticleTurkish journal of biology = Turk biyoloji dergisi2022

Design and in vitro, in vivo evaluation of antioxidant bioadhesive gels for burn treatment.

Göksel Gökçe, Sinem Yaprak Karavana, Alper Bağriyanik, Çetin Pekçetin, Evren Algin Yapar, Gülşen Aybar Tural, Evren Homan Gökçe

Abstract read
In one paragraph

Article in Turkish journal of biology = Turk biyoloji dergisi, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Göksel GökçeDepartment of Pharmacology, Faculty of Pharmacy, Ege University, Bornova, İzmir, Turkey.ORCID https://orcid.org/0000-0001-5328-1086
Sinem Yaprak KaravanaDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Ege University, Bornova, İzmir, Turkey.ORCID https://orcid.org/0000-0001-6010-5902
Alper BağriyanikDepartment of Histology-Embryology, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.ORCID https://orcid.org/0000-0003-4064-7637
Çetin PekçetinDepartment of Histology-Embryology, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.ORCID https://orcid.org/0000-0002-9406-1714
Evren Algin YaparDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Cumhuriyet University, Sivas, Turkey.ORCID https://orcid.org/0000-0002-6504-4608
Gülşen Aybar TuralDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Ege University, Bornova, İzmir, Turkey.ORCID https://orcid.org/0000-0001-9786-5681
Evren Homan GökçeDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Ege University, Bornova, İzmir, Turkey.ORCID https://orcid.org/0000-0002-0751-5563

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Burn wounds are frequently encountered health problems, which need a new treatment approach especially in terms of good patient compliance. Availability of use of antioxidant agents and bio-adhesive gels in tissue healing can be an alternative as a new approach for wound healing. Antioxidant taurine containing bio-adhesive gels were prepared by using carbopol (CP) 940 and 934. Rheological and texture analyses were carried out on bio-adhesive gels for in vitro characterization. Wound model on Wistar rats was used to evaluate the in vivo evaluation of gels. Rheological and texture analyses showed that a carbopol bioadhesive gel has acceptable topically use dosage characteristics and in combination with Taurine it presented a successful wound healing effect via antioxidant parameters. In conclusion, bio-adhesive CP 940 (2%) gel containing 50 mM taurine could be promising in the treatment of burns by balancing oxidative stress.

Indexed as

antioxidantbio-adhesive gelburn wound modelTaurine

Identifiers

PMID37529259
PMCPMC10388085

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.