Evidence map›Paper›PMID 37529256›Full record

ReviewTurkish journal of biology = Turk biyoloji dergisi2022

Point-of-care diagnosis of cervical cancer: potential protein biomarkers in cervicovaginal fluid.

Büşra Köse, Özgüç Takmaz, Mete Güngör, Ahmet Tarık Baykal

Abstract readReview
In one paragraph

Review in Turkish journal of biology = Turk biyoloji dergisi, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Büşra KöseDepartment of Biochemistry and Molecular Biology, Institute of Health Sciences, University of Acıbadem Mehmet Ali Aydınlar, İstanbul, Turkey.ORCID https://orcid.org/0000-0001-7043-390X
Özgüç TakmazSchool of Medicine, Department of Obstetrics and Gynecology, University of Acıbadem Mehmet Ali Aydınlar, İstanbul, Turkey.ORCID https://orcid.org/0000-0002-3397-7980
Mete GüngörSchool of Medicine, Department of Obstetrics and Gynecology, University of Acıbadem Mehmet Ali Aydınlar, İstanbul, Turkey.ORCID https://orcid.org/0000-0001-8010-4181
Ahmet Tarık BaykalSchool of Medicine, Department of Medical Biochemistry, University of Acıbadem Mehmet Ali Aydınlar, İstanbul, Turkey.ORCID https://orcid.org/0000-0002-8814-7351

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer (CxCa) is preventable and treatable via vaccination and screening. Cervicovaginal fluid (CVF) represents the physiological components of the female genital tract. These components are suitable to be utilized for clinical purposes, therefore, making CVF a suitable material for disease screening approaches. Due to high false-negative result rates and low attendance of current expensive routine CxCa screening methods, it has become more important to develop a point-of-care (POC) screening method that every single woman could reach worldwide. For this purpose, various self-usage apparatus have been developed for screening of the human papilloma virus (HPV) infection. Furthermore, due to the low specificity of HPV tests and the high clearance rate of HPV infections, many patients undergo overtreatment. Since proteins play an important role in cellular process and carcinogenesis, it is appropriate to use proteins in a simple screening test for the detection of carcinogenesis. In this article, POC screening tests and the studies of discovery of CVF protein biomarkers will be overviewed to consider the development of a method that can be used for the rapid and conceivable screening method of CxCa.

Indexed as

biosensorCervical cancercervicovaginal fluidprotein biomarkerproteomics

Identifiers

PMID37529256
PMCPMC10387838

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.