Evidence map›Paper›PMID 37529237›Full record

ArticleFrontiers in cell and developmental biology2023

Recognition of H2AK119ub plays an important role in RSF1-regulated early

Saeid Mohammad Parast, Deli Yu, Chunxu Chen, Amanda J Dickinson, Chenbei Chang, Hengbin Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Polycomb Repressive Complex 1 and USP16 localize to the mitochondrion and influence its function.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Saeid Mohammad ParastDepartment of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, United States.
Deli YuDepartment of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, United States.
Chunxu ChenDepartment of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL, United States.
Amanda J DickinsonDepartment of Biology, College of Humanities and Sciences, Virginia Commonwealth University, Richmond, VA, United States.
Chenbei ChangDepartment of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, United States.
Hengbin WangDepartment of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL, United States.
University of Alabama at Birmingham · USVirginia Commonwealth University · US

Funding

Remodeling and Spacing Factor 1 in Histone H2A Ubiquitination-Mediated Gene SilencingR01GM130696 · NIGMS · VIRGINIA COMMONWEALTH UNIVERSITY · PI WANG, HENGBIN · 2019 to 2020
$593k
NIGMS NIH HHS R01 GM130696
6 · The paper itself

Abstract

Polycomb group (PcG) proteins are key regulators of gene expression and developmental programs via covalent modification of histones, but the factors that interpret histone modification marks to regulate embryogenesis are less studied. We previously identified Remodeling and Spacing Factor 1 (RSF1) as a reader of histone H2A lysine 119 ubiquitination (H2AK119ub), the histone mark deposited by Polycomb Repressive Complex 1 (PRC1). In the current study, we used

Indexed as

developmentH2AK119ubmesodermneural and neural crestPRC1RSF1UAB domainXenopus laevis

Identifiers

PMID37529237
PMCPMC10389277
OpenAlexW4384499961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.