ArticleTurkish journal of chemistry2023
Dual-reactive hydrogels functionalizable using "Huisgen click" and "Schiff base" reactions.
Article in Turkish journal of chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Functionalized polysaccharides for infection-resistant and regenerative therapies in gynecology.International journal of pharmaceutics: X · 2026Review
- Synthesis of isocyanate containing cryogels for fast (bio)molecular immobilization.Turkish journal of chemistry · 2024Article
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Abstract
Hydrogels incorporating different reactive groups are important platforms for the fabrication of functional materials through the conjugation of diverse molecules. In this study, a dual-reactive hydrogel system was designed utilizing aldehyde and azide groups containing methacrylate monomers. Hydrogels were obtained in the presence of a dimethacrylate crosslinker with a combination of hydrophilic PEG-based monomers via free-radical polymerization. The azide and aldehyde sites of the hydrogel network are reactive towards alkyne and amine functional groups, respectively. The advantage of the different reactivities of these functional groups was demonstrated through the attachment of two different dye molecules onto the hydrogel platform via the "Huisgen click" and "Schiff base" reactions to obtain a sensing platform for various applications, such as indicating change in pH of the environment.
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