Evidence map›Paper›PMID 37529119›Full record

ArticleCurrent developments in nutrition2023

Quantification of the Relationship of Pyridoxine and Spirometry Measurements in the United States Population.

Alexander A Huang, Samuel Y Huang

Abstract read
In one paragraph

Article in Current developments in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alexander A HuangCornell University, Ithaca, New York.
Samuel Y HuangCornell University, Ithaca, New York.

Funding

The Northwestern Summer Research Program for Medical StudentsT35DK126628 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniela P Ladner · 2021 to 2026
$302k
NIDDK NIH HHS T35 DK126628
6 · The paper itself

Abstract

Background: There has been evidence to suggest associations between vitamins and lung function. Objective: This study aimed to examine the association between vitamin B6 and spirometry values. Methods: A cross-sectional study was done using National Health and Nutritional Examination Surveys (NHANES) 2007-2012, which is a nationally representative, modern cohort. Spirometry, a clinical pulmonary function test, measured the amount and speed of air a person could exhale after taking the deepest possible breath after forceful expiratory volume at 1 s (FEV1) and forced vital capacity (FVC). After determination of the relationship of the linearity of variables, univariable and multivariable models were fitted to investigate the effect of vitamin B6 on FEV1 and FVC. The National Center for Health Statistics Ethics Review Board granted permission for the study's data collection and analysis. Results: Of 19,160 individuals who had complete information on vitamin B6 intake, FEV1, and FVC, it was found each mg of vitamin B6 intake was associated with increase in 166.41 mL of FEV1 (95% CI: 156.71, 176.12; Conclusion: Increased vitamin B6 intake is associated with improvement in lung function. Further prospective studies are required to ascertain whether increased vitamin B6 can lead to increased long-term spirometry measurements and the specific therapeutic dose-response relationship.

Indexed as

NHANESregressionspirometrysplinevitamin B6

Identifiers

PMID37529119
PMCPMC10387570

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.