ArticleiScience2023
Characterization of the primary structure of the major silk gene,
Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Morphological and compositional basis of silk fiber function inJournal of materials chemistry. B · 2026Article
- On the dynamic caddisfly silk H-fibroin gene: a population study in a net-spinning species.Molecular biology and evolution · 2026Article
- Post-translational modifications of silk proteins.RSC chemical biology · 2026Review
- Genomics of Caddisfly (Insecta: Trichoptera) Species Associated With Terrestrial Habitats.Ecology and evolution · 2026Article
- Evolution of Highly Repetitive Silk Genes in the Luna Moth, Actias luna.Genome biology and evolution · 2026Article
- Design and Heterologous Production of Bagworm Silk-Inspired Proteins inComputational and structural biotechnology journal · 2026Article
- Life inside a bag: multiomics insights into the bagworm species Eumeta crameri.DNA research : an international journal for rapid publication of reports on genes and genomes · 2025Article
- Triangle weaver spiders construct spring-loaded webs using a novel set of genes for exceptionally proline-rich silk.PNAS nexus · 2025Article
- De Novo Whole Genome Assemblies of Unusual Case-Making Caddisflies (Trichoptera) Highlight Genomic Convergence in the Composition of the Major Silk Gene (h-fibroin).Journal of experimental zoology. Part B, Molecular and developmental evolution · 2025Article
- Native Silk Fibers: Protein Sequence and Structure Influences on Thermal and Mechanical Properties.Biomacromolecules · 2025Review
- Absence of fibroin H sequences and a significant divergence in the putative fibroin L homolog in Neomicropteryx cornuta (Micropterigidae) silk.Communications biology · 2025Article
- Genomic resources of aquatic Lepidoptera, Elophila obliteralis and Hyposmocoma kahamanoa, reveal similarities with Trichoptera in amino acid composition of major silk genes.G3 (Bethesda, Md.) · 2024Article
- Evolution of Opsin Genes in Caddisflies (Insecta: Trichoptera).Genome biology and evolution · 2024Article
- De Novo Long-Read Genome Assembly and Annotation of the Luna Moth (Actias luna) Fully Resolves Repeat-Rich Silk Genes.Genome biology and evolution · 2024Article
- Comprehensive analysis of silk proteins and gland compartments in Limnephilus lunatus, a case-making trichopteran.BMC genomics · 2024Article
- Chromosome-scale genome assemblies of Himalopsyche anomala and Eubasilissa splendida (Insecta: Trichoptera).Scientific data · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Larvae of caddisflies (Trichoptera) produce silk to build various underwater structures allowing them to exploit a wide range of aquatic environments. The silk adheres to various substrates underwater and has high tensile strength, extensibility, and toughness and is of interest as a model for biomimetic adhesives. As a step toward understanding how the properties of underwater silk evolved in Trichoptera, we used genomic data to identify full-length sequences and characterize the primary structure of the major silk protein, h-fibroin, across the order. The h-fibroins have conserved termini and basic motif structure with high variation in repeating modules and variation in the percentage of amino acids, mainly proline. This finding might be linked to differences in mechanical properties related to the different silk usage and sets a starting point for future studies to screen and correlate amino acid motifs and other sequence features with quantifiable silk properties.
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