Evidence map›Paper›PMID 37528943›Full record

ArticleJournal of clinical and translational science2023

Challenges and strategies for recruitment of minorities to clinical research and trials.

Susan P Fisher-Hoch, Jennifer E Below, Kari E North, Joseph B McCormick

Abstract read
In one paragraph

Article in Journal of clinical and translational science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  14. Scientia pro bono humani generis: Science for the benefit of humanity.Journal of clinical and translational science · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Susan P Fisher-HochUTHealth Houston School of Public Health, Brownsville Campus, Brownsville, TX, USA.
Jennifer E BelowVanderbilt University Medical Center, Division of Genetic Medicine, Nashville, TN, USA.
Kari E NorthUniversity of North Carolina Gillings School of Global Public Health, Chapel Hill, NC, USA.
Joseph B McCormickUTHealth Houston School of Public Health, Brownsville Campus, Brownsville, TX, USA.ORCID https://orcid.org/0000-0002-5844-8102

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Hazel B Nichols · 2001 to 2026
$36.3M
Hispanic Latino Lipid ConsortiumR01HL142302 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jennifer Below, JOSEPH MCCORMICK · 2018 to 2026
$5.8M
Leveraging Hispanic/Latino diversity to map and characterize cardiovascular disease lociR01HL163262 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Lindsay Fernandez-Rhodes, Mariaelisa Graff · 2023 to 2026
$2.9M
NHLBI NIH HHS R01 HL142302NHLBI NIH HHS R01 HL163262NIEHS NIH HHS P30 ES010126
6 · The paper itself

Abstract

Minority populations are largely absent from clinical research trials. The neglect of these populations has become increasingly apparent, with escalating cancer burdens and chronic disease. The challenges to recruitment of minorities in the United States are multiple including trust or lack thereof. Keys to successful recruitment are responding to community issues, its history, beliefs, and its social and economic pressures. The strategy we have used in many low-income, sometimes remote, communities is to recruit staff from the same community and train them in the required basic research methods. They are the first line of communication. After our arrival in the Texas Rio Grande Valley in 2001, we applied these principles learned over years of global research, to studies of chronic diseases. Beginning in 2004, we recruited and trained a team of local women who enrolled in a cohort of over five thousand Mexican Americans from randomly selected households. This cohort is being followed, and the team has remained, acquiring not only advanced skills (ultrasound, FibroScan, retinal photos, measures of cognition, etc.) but capacity to derive key health information. Currently, we are participating in multiple funded studies, including an NIH clinical trial, liver disease, obesity, and diabetes using multiomics aimed at developing precision medicine approaches to chronic disease prevention and treatment.

Indexed as

Chronic diseasecommunity engagementhealth disparitiesminority clinical studiesRecruitment

Identifiers

PMID37528943
PMCPMC10388414

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.