Evidence map›Paper›PMID 37528519›Full record

SynthesisNursing open2023

Pregnancy rate, maternal and neonatal outcomes among breast cancer survivors: A systematic review.

Marzieh Azizi, Elham Ebrahimi, Zahra Behboodi Moghadam, Zohreh Shahhosseini, Maryam Modarres

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Nursing open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 4 pooled it
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 4 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pregnancy after cancer: FIGO Best practice advice.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Guideline
  3. Pooled it
  4. Pooled it
  5. Review
  6. Review
  7. Article
  8. Estrogens and breast cancer.Annals of oncology : official journal of the European Society for Medical Oncology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Marzieh AziziDepartment of Midwifery and Reproductive Health, School of Nursing & Midwifery, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-0835-3201
Elham EbrahimiDepartment of Midwifery and Reproductive Health, School of Nursing & Midwifery, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-9767-5797
Zahra Behboodi MoghadamDepartment of Midwifery and Reproductive Health, School of Nursing & Midwifery, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-4708-3590
Zohreh ShahhosseiniDepartment of Midwifery, School of Nursing and Midwifery, Sexual and Reproductive Health Research Center, Mazandaran University of Medical Sciences, Sari, Iran.ORCID 0000-0003-1288-2277
Maryam ModarresDepartment of Midwifery and Reproductive Health, Researcher of Nursing and Midwifery Care Research Center, School of Nursing & Midwifery, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0003-0042-7023
Tehran University of Medical Sciences · IRIranshahr University · IRIran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis study investigated the pregnancy rate, maternal and neonatal outcomes, and breast cancer (BC) recurrence status after pregnancy among BC survivors.

designA systematic review.

methodsElectronic databases such as PubMed, Web of Science [WOS], Scopus, ScienceDirect, Google Scholar, and Scientific Information Database were systematically searched. The quality of included studies was evaluated using the Newcastle-Ottawa Scale (NOS). Observational studies reported the pregnancy rate, maternal and neonatal outcomes among reproductive-aged BC survivors, and the recurrence status of BC after pregnancy were eligible to include in this study.

resultsOf the 29 included studies, 13 studies were prospective cohorts or prospective multicenter or population-based cohorts, 14 studies were retrospective cohort or retrospective population-based cohort studies, and two studies were cross-sectional retrospective surveys or population-based descriptive studies. This systematic review showed that the pregnancy rate was estimated at 3.1%-48.5% among BC survivors who attempted to conceive. The most prevalent maternal outcomes of pregnancy were miscarriage (1.8%-33.3%) and induced abortion (5.0%-44%) as well as preterm birth (PTB) or very PTB (1.2%-21.1%), and twin birth (1.1%-38.8%) were the most prevalent neonatal outcomes occurring among BC survivors, respectively. In addition, most of the included studies indicated that pregnancy had no adverse effect on the status of BC recurrence among survivors. Surviving women can be encouraged and receive a carefully multidisciplinary approach regarding healthy pregnancy. No Patient or Public Contribution.

Indexed as

Breast NeoplasmsCancer SurvivorsPremature BirthAdultFemaleHumansInfant, NewbornMulticenter Studies as TopicNeoplasm Recurrence, LocalObservational Studies as TopicPregnancyPregnancy RateProspective StudiesRetrospective Studiesbreast cancerpregnancy outcomeprevalencesurvivors

Identifiers

PMID37528519
PMCPMC10495738
OpenAlexW4385476220

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.