Evidence map›Paper›PMID 37528508›Full record

ArticleInternational wound journal2023

Predilection sites of pyoderma gangrenosum: Retrospective study of 170 clearly diagnosed patients.

Maurice Moelleken, Cornelia Erfurt-Berge, Moritz Ronicke, Dorothee Busch, Ursula Hertha Hübner, Jens Hüsers, Mareike Przysucha, Joachim Dissemond

Open access · goldAbstract read
In one paragraph

Article in International wound journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. [Pyoderma gangrenosum: pathogenesis, diagnosis, and treatment].Dermatologie (Heidelberg, Germany) · 2025
    Review
  6. Article
  7. The Differential Diagnosis of Leg Ulcers.Deutsches Arzteblatt international · 2024
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Maurice MoellekenDepartment of Dermatology, Venerology and Allergology, University Hospital of Essen, Essen, Germany.ORCID https://orcid.org/0000-0002-5517-8696
Cornelia Erfurt-BergeDepartment of Dermatology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.ORCID https://orcid.org/0000-0002-3722-6383
Moritz RonickeDepartment of Dermatology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.ORCID https://orcid.org/0000-0001-8828-0980
Dorothee BuschDepartment of Dermatology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
Ursula Hertha HübnerHealth Informatics Research Group, Osnabrück University of AS, Osnabrück, Germany.
Jens HüsersHealth Informatics Research Group, Osnabrück University of AS, Osnabrück, Germany.
Mareike PrzysuchaHealth Informatics Research Group, Osnabrück University of AS, Osnabrück, Germany.
Joachim DissemondDepartment of Dermatology, Venerology and Allergology, University Hospital of Essen, Essen, Germany.ORCID https://orcid.org/0000-0003-3893-328X
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEOsnabrück University · DEEssen University Hospital · DE

Funding

Bundesministerium für Bildung und Forschung 16SV8616
6 · The paper itself

Abstract

Pyoderma gangrenosum (PG) is a non-infectious, neutrophilic dermatosis that was difficult to diagnose in clinical practice. Today, the PARACELSUS score is a validated tool for diagnostics. Based on this score, patients with clearly diagnosed PG were examined with regard to predilection sites. In this retrospective study, the data of patients from the University Hospitals of Essen and Erlangen were analysed in whom the diagnosis of PG could be clearly confirmed using the PARACELSUS score. A total of 170 patients, 49 men (29%) and 121 women (71%) with an average age at first manifestation of 55.5 years, could be included in the analysis. The predilection sites were identified as the lower legs in 80.6% of the patients and the extensor sides in 75.2%. Other localisations of PG were the thighs in 14.1%, mammae and abdomen in 10.0% each, back and gluteal in 7.1% each, feet in 5.9%, arms in 4.7%, genital in 3.5% and head in 2.9%. This retrospective study is the first to identify a collective of PG patients with the highest data quality using the PARACELSUS score. It could be shown that PG can basically occur on the entire integument. However, the predilection sites of PG, which have now been reliably identified for the first time, are the lower legs and in particular the extensor sides.

Indexed as

Pyoderma GangrenosumDiagnosis, DifferentialFemaleFootHospitals, UniversityHumansMaleMiddle AgedRetrospective Studieschronic woundsleg ulcerPARACELSUS scorepredilection sitespyoderma gangrenosum

Identifiers

PMID37528508
PMCPMC10681478
OpenAlexW4385477601

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.