Evidence map›Paper›PMID 37528328›Full record

ArticleInternal and emergency medicine2023

MAGLIO study: epideMiological Analysis on invasive meninGococcaL disease in Italy: fOcus on hospitalization from 2015 to 2019.

Carlo Tascini, Raffaella Iantomasi, Francesco Sbrana, Ciro Carrieri, Daniela D'Angela, Silvia Cocchio, Barbara Polistena, Federico Spandonaro, Eva Agostina Montuori, Vincenzo Baldo

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal and emergency medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Carlo TasciniU.O. Malattie Infettive, Dipartimento di Medicina dell'Università di Udine, Università di Udine e Azienda Sanitaria Universitaria Integrata di Udine, Via Pozzuolo, 330, 33100, Udine, Italy. carlo.tascini@uniud.it.
Raffaella IantomasiVaccine Medical Department, Pfizer, Rome, Italy.
Francesco SbranaU.O. Lipoapheresis and Center for Inherited Dyslipidemias, Fondazione Toscana Gabriele Monasterio, Pisa, Italy.ORCID 0000-0003-4607-0373
Ciro CarrieriC.R.E.A. Sanità e Università di Roma Tor Vergata, Rome, Italy.
Daniela D'AngelaC.R.E.A. Sanità e Università di Roma Tor Vergata, Rome, Italy.
Silvia CocchioDepartment of Cardiac Thoracic Vascular Sciences and Public Health, Public Health Section, University of Padua, Via Leonardo Loredan 18, 35131, Padua, Italy.
Barbara PolistenaC.R.E.A. Sanità e Università di Roma Tor Vergata, Rome, Italy.
Federico SpandonaroUniversità Telematica San Raffaele di Roma e C.R.E.A. Sanità, Rome, Italy.
Eva Agostina MontuoriVaccine Medical Department, Pfizer, Rome, Italy.
Vincenzo BaldoDepartment of Cardiac Thoracic Vascular Sciences and Public Health, Public Health Section, University of Padua, Via Leonardo Loredan 18, 35131, Padua, Italy.
University of Rome Tor Vergata · ITPfizer (Italy) · ITUniversity of Padua · ITFondazione Toscana Gabriele Monasterio · ITSan Raffaele University of Rome · ITUniversity of Udine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study analyzed hospital admissions for invasive meningococcal disease (IMD) in epidemiological and economic terms in Italy from 2015 to 2019. The volume of acute admissions for meningococcal diagnosis was analyzed in the period from 2015 to 2019. IMD admissions were identified by ICD-9-CM diagnoses. Costs were assessed using current DRG tariffs. In 2019, a total of 237 admissions for meningococcal disease were recorded in Italy. The mean age of patients was 36.1 years. Lumbar puncture was reported in only 14% of hospital discharge forms. From 2015 to 2019, there was a mean annual reduction of - 1.2% nationally for IMD hospitalizations. For 2019, the total costs for acute inpatient admissions were €2,001,093. Considering annual incidence due to IMD, a significant decrease was noted in the age group from 0 to 1 year (p = 0.010) during 2015-2019. For all years, mortality associated with meningeal syndrome was lower compared to septic shock with or without meningitis. From 2015 to 2019, hospitalizations for IMD appear to be decreasing slightly in Italy, even if mortality remains high. Favorable trends in hospitalizations for IMD were seen in the 0-1-year age group, which may be attributable to increased vaccination. Costs of hospitalizations for IMD remain high.

Indexed as

Meningococcal InfectionsNeisseria meningitidisAdultHospitalizationHumansIncidenceInfantItalyPatient DischargeCostsHospitalizationInvasive meningococcal diseaseItalyMortality

Identifiers

PMID37528328
PMCPMC10543787
OpenAlexW4385450608

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.