Evidence map›Paper›PMID 37528314›Full record

ArticleCell biochemistry and biophysics2023

NSUN5-FTH1 Axis Inhibits Ferroptosis to Promote the Growth of Gastric Cancer Cells.

Yibin Su, Jiangrui Liu, Zhihua Zheng, Liangpan Shi, Wenchang Huang, Xiaohui Huang, Chengwei Ye, Jinyu Qi, Weidong Wang, Haibin Zhuang

Abstract read
PubMed Publisher
In one paragraph

Article in Cell biochemistry and biophysics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. NSUN5 promotes cholangiocarcinoma progression by enhancing GLS mRNA stabilization.Journal of cancer research and clinical oncology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yibin Su *Department of Gastrointestinal Surgery, Quanzhou First Hospital affiliated to Fujian Medical University, No. 248 East Street, Licheng District, Quanzhou, 362000, Fujian, China. suyibin110@fjmu.edu.cn.
Jiangrui Liu *Department of Gastrointestinal Surgery, Quanzhou First Hospital affiliated to Fujian Medical University, No. 248 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Zhihua ZhengDepartment of Gastrointestinal Surgery, Quanzhou First Hospital affiliated to Fujian Medical University, No. 248 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Liangpan ShiDepartment of Gastrointestinal Surgery, Quanzhou First Hospital affiliated to Fujian Medical University, No. 248 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Wenchang HuangDepartment of Gastrointestinal Surgery, Quanzhou First Hospital affiliated to Fujian Medical University, No. 248 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Xiaohui HuangDepartment of Gastrointestinal Surgery, Quanzhou First Hospital affiliated to Fujian Medical University, No. 248 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Chengwei YeDepartment of Gastrointestinal Surgery, Quanzhou First Hospital affiliated to Fujian Medical University, No. 248 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Jinyu QiDepartment of Gastrointestinal Surgery, Quanzhou First Hospital affiliated to Fujian Medical University, No. 248 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Weidong WangDepartment of Gastrointestinal Surgery, Quanzhou First Hospital affiliated to Fujian Medical University, No. 248 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Haibin ZhuangDepartment of Gastrointestinal Surgery, Quanzhou First Hospital affiliated to Fujian Medical University, No. 248 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies revealed that NOP2/Sun RNA methyltransferase 5 (NSUN5) - ferritin heavy chain (FTH1) pathway is associated with ferroptosis in stem cells, whereas its roles in gastric cancer are still unclear. Our study aims to investigate the roles of the NSUN5-FTH1 axis in gastric cancer (GC) and its molecular mechanisms. Stable cell lines were constructed on SGC7901 cells by using shRNAs and pcDNA3.1 expression vectors, respectively. CCK-8 kits were used to determine cell viability. Biochemicals assays were used to detect lipid reactive oxygen species (ROS) and intracellular Fe

Indexed as

FerroptosisStomach NeoplasmsAnimalsDisease Models, AnimalFerritinsHumansLipidsMethyltransferasesMiceMuscle ProteinsOxidoreductasesReactive Oxygen SpeciesRNA, Small InterferingFerritinsFTH1 protein, humanLipidsMethyltransferasesMuscle ProteinsNSUN5 protein, humanOxidoreductasesReactive Oxygen SpeciesRNA, Small InterferingFerroptosisGastric cancerNSUN5NSUN5-FTH1 axisTumor growth

Identifiers

PMID37528314
OpenAlexW4385463364

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.