Evidence map›Paper›PMID 37526874›Full record

ArticleJournal of fluorescence2024

Exploring the pH-Responsive Interaction of β-Blocker Drug Propranolol with Biomimetic Micellar Media: Fluorescence and Electronic Absorption Studies.

Nurendra Chhetri, Moazzam Ali

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of fluorescence, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nurendra ChhetriDepartment of Chemistry, Sikkim Manipal Institute of Technology, Sikkim Manipal University, Sikkim, India.
Moazzam AliDepartment of Chemistry, Sikkim Manipal Institute of Technology, Sikkim Manipal University, Sikkim, India. moazzam.a@smit.smu.edu.in.
Sikkim Manipal University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interaction of neutral and charged lipophilic beta-blocker drug, propranolol (PPL) with biomimicking nanocavities formed by micelles bearing same and opposite charges namely, cationic cetyltrimethylammonium bromide (CTAB), a surface-active ionic liquid 1-hexadecyl-3-methylimidazolium chloride (HDMIC) and anionic sodium dodecyl sulphate (SDS) have been investigated using fluorescence and absorption spectroscopic techniques. Binding of PPL to SDS at pH < pKa is characterised by biphasic interactions with decrease in fluorescence intensity at lower concentrations and subsequent increase post micellization. All the surfactants show significant interactions with the neutral drug molecule at pH > pKa, which is evident from the strongest binding constant (

Indexed as

Adrenergic beta-AntagonistsMicellesPropranololSodium Dodecyl SulfateSpectrometry, FluorescenceBiomimetic MaterialsCetrimoniumElectronsHydrogen-Ion ConcentrationSurface-Active AgentsAdrenergic beta-AntagonistsCetrimoniumMicellesPropranololSodium Dodecyl SulfateSurface-Active AgentsBindingMicellespHPropranololQuenching

Identifiers

PMID37526874
OpenAlexW4385442946

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.