Evidence map›Paper›PMID 37526539›Full record

Trial reportRadiology2023

Evaluating Radiation Exposure in Patients with Stable Chest Pain in the SCOT-HEART Trial.

Justin Chiong, Prasad Guntur Ramkumar, Nicholas W Weir, Jonathan R Weir-McCall, Alberto Nania, Leslee J Shaw, Andrew J Einstein, Marc R Dweck, Nicholas L Mills, David E Newby and 3 more

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in Radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Justin ChiongFrom the British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, UK (J.C., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); Department of Radiology, Ninewells Hospital, Dundee, UK (P.G.R.); Clinical Research Imaging Facility, University of Dundee, UK (P.G.R.); Department of Medical Physics, NHS Lothian, Edinburgh, UK (N.W.W.); Edinburgh Imaging Facility QMRI, University of Edinburgh, Edinburgh, UK (N.W.W., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); University of Cambridge, Cambridge, UK (J.R.W.M.); Royal Papworth Hospital, Cambridge, UK (J.R.W.M.); Department of Radiology, Royal Infirmary of Scotland, Edinburgh, UK (A.N., E.J.R.v.B., M.C.W.); Blavatnik Family Women's Health Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY (L.J.S.); Seymour, Paul and Gloria Milstein Division of Cardiology, Department of Medicine, and Department of Radiology, Columbia University Irving Medical Center and New York-Presbyterian Hospital, New York, NY (A.J.E.); and Institute of Clinical Sciences, University of Glasgow, UK (G.R.).ORCID 0000-0003-3795-5639
Prasad Guntur RamkumarFrom the British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, UK (J.C., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); Department of Radiology, Ninewells Hospital, Dundee, UK (P.G.R.); Clinical Research Imaging Facility, University of Dundee, UK (P.G.R.); Department of Medical Physics, NHS Lothian, Edinburgh, UK (N.W.W.); Edinburgh Imaging Facility QMRI, University of Edinburgh, Edinburgh, UK (N.W.W., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); University of Cambridge, Cambridge, UK (J.R.W.M.); Royal Papworth Hospital, Cambridge, UK (J.R.W.M.); Department of Radiology, Royal Infirmary of Scotland, Edinburgh, UK (A.N., E.J.R.v.B., M.C.W.); Blavatnik Family Women's Health Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY (L.J.S.); Seymour, Paul and Gloria Milstein Division of Cardiology, Department of Medicine, and Department of Radiology, Columbia University Irving Medical Center and New York-Presbyterian Hospital, New York, NY (A.J.E.); and Institute of Clinical Sciences, University of Glasgow, UK (G.R.).ORCID 0000-0003-2168-3739
Nicholas W WeirFrom the British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, UK (J.C., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); Department of Radiology, Ninewells Hospital, Dundee, UK (P.G.R.); Clinical Research Imaging Facility, University of Dundee, UK (P.G.R.); Department of Medical Physics, NHS Lothian, Edinburgh, UK (N.W.W.); Edinburgh Imaging Facility QMRI, University of Edinburgh, Edinburgh, UK (N.W.W., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); University of Cambridge, Cambridge, UK (J.R.W.M.); Royal Papworth Hospital, Cambridge, UK (J.R.W.M.); Department of Radiology, Royal Infirmary of Scotland, Edinburgh, UK (A.N., E.J.R.v.B., M.C.W.); Blavatnik Family Women's Health Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY (L.J.S.); Seymour, Paul and Gloria Milstein Division of Cardiology, Department of Medicine, and Department of Radiology, Columbia University Irving Medical Center and New York-Presbyterian Hospital, New York, NY (A.J.E.); and Institute of Clinical Sciences, University of Glasgow, UK (G.R.).
Jonathan R Weir-McCallFrom the British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, UK (J.C., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); Department of Radiology, Ninewells Hospital, Dundee, UK (P.G.R.); Clinical Research Imaging Facility, University of Dundee, UK (P.G.R.); Department of Medical Physics, NHS Lothian, Edinburgh, UK (N.W.W.); Edinburgh Imaging Facility QMRI, University of Edinburgh, Edinburgh, UK (N.W.W., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); University of Cambridge, Cambridge, UK (J.R.W.M.); Royal Papworth Hospital, Cambridge, UK (J.R.W.M.); Department of Radiology, Royal Infirmary of Scotland, Edinburgh, UK (A.N., E.J.R.v.B., M.C.W.); Blavatnik Family Women's Health Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY (L.J.S.); Seymour, Paul and Gloria Milstein Division of Cardiology, Department of Medicine, and Department of Radiology, Columbia University Irving Medical Center and New York-Presbyterian Hospital, New York, NY (A.J.E.); and Institute of Clinical Sciences, University of Glasgow, UK (G.R.).ORCID 0000-0001-5842-842X
Alberto NaniaFrom the British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, UK (J.C., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); Department of Radiology, Ninewells Hospital, Dundee, UK (P.G.R.); Clinical Research Imaging Facility, University of Dundee, UK (P.G.R.); Department of Medical Physics, NHS Lothian, Edinburgh, UK (N.W.W.); Edinburgh Imaging Facility QMRI, University of Edinburgh, Edinburgh, UK (N.W.W., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); University of Cambridge, Cambridge, UK (J.R.W.M.); Royal Papworth Hospital, Cambridge, UK (J.R.W.M.); Department of Radiology, Royal Infirmary of Scotland, Edinburgh, UK (A.N., E.J.R.v.B., M.C.W.); Blavatnik Family Women's Health Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY (L.J.S.); Seymour, Paul and Gloria Milstein Division of Cardiology, Department of Medicine, and Department of Radiology, Columbia University Irving Medical Center and New York-Presbyterian Hospital, New York, NY (A.J.E.); and Institute of Clinical Sciences, University of Glasgow, UK (G.R.).
Leslee J ShawFrom the British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, UK (J.C., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); Department of Radiology, Ninewells Hospital, Dundee, UK (P.G.R.); Clinical Research Imaging Facility, University of Dundee, UK (P.G.R.); Department of Medical Physics, NHS Lothian, Edinburgh, UK (N.W.W.); Edinburgh Imaging Facility QMRI, University of Edinburgh, Edinburgh, UK (N.W.W., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); University of Cambridge, Cambridge, UK (J.R.W.M.); Royal Papworth Hospital, Cambridge, UK (J.R.W.M.); Department of Radiology, Royal Infirmary of Scotland, Edinburgh, UK (A.N., E.J.R.v.B., M.C.W.); Blavatnik Family Women's Health Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY (L.J.S.); Seymour, Paul and Gloria Milstein Division of Cardiology, Department of Medicine, and Department of Radiology, Columbia University Irving Medical Center and New York-Presbyterian Hospital, New York, NY (A.J.E.); and Institute of Clinical Sciences, University of Glasgow, UK (G.R.).ORCID 0000-0003-1268-1491
Andrew J EinsteinFrom the British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, UK (J.C., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); Department of Radiology, Ninewells Hospital, Dundee, UK (P.G.R.); Clinical Research Imaging Facility, University of Dundee, UK (P.G.R.); Department of Medical Physics, NHS Lothian, Edinburgh, UK (N.W.W.); Edinburgh Imaging Facility QMRI, University of Edinburgh, Edinburgh, UK (N.W.W., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); University of Cambridge, Cambridge, UK (J.R.W.M.); Royal Papworth Hospital, Cambridge, UK (J.R.W.M.); Department of Radiology, Royal Infirmary of Scotland, Edinburgh, UK (A.N., E.J.R.v.B., M.C.W.); Blavatnik Family Women's Health Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY (L.J.S.); Seymour, Paul and Gloria Milstein Division of Cardiology, Department of Medicine, and Department of Radiology, Columbia University Irving Medical Center and New York-Presbyterian Hospital, New York, NY (A.J.E.); and Institute of Clinical Sciences, University of Glasgow, UK (G.R.).ORCID 0000-0003-2583-9278
Marc R DweckFrom the British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, UK (J.C., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); Department of Radiology, Ninewells Hospital, Dundee, UK (P.G.R.); Clinical Research Imaging Facility, University of Dundee, UK (P.G.R.); Department of Medical Physics, NHS Lothian, Edinburgh, UK (N.W.W.); Edinburgh Imaging Facility QMRI, University of Edinburgh, Edinburgh, UK (N.W.W., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); University of Cambridge, Cambridge, UK (J.R.W.M.); Royal Papworth Hospital, Cambridge, UK (J.R.W.M.); Department of Radiology, Royal Infirmary of Scotland, Edinburgh, UK (A.N., E.J.R.v.B., M.C.W.); Blavatnik Family Women's Health Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY (L.J.S.); Seymour, Paul and Gloria Milstein Division of Cardiology, Department of Medicine, and Department of Radiology, Columbia University Irving Medical Center and New York-Presbyterian Hospital, New York, NY (A.J.E.); and Institute of Clinical Sciences, University of Glasgow, UK (G.R.).
Nicholas L MillsFrom the British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, UK (J.C., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); Department of Radiology, Ninewells Hospital, Dundee, UK (P.G.R.); Clinical Research Imaging Facility, University of Dundee, UK (P.G.R.); Department of Medical Physics, NHS Lothian, Edinburgh, UK (N.W.W.); Edinburgh Imaging Facility QMRI, University of Edinburgh, Edinburgh, UK (N.W.W., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); University of Cambridge, Cambridge, UK (J.R.W.M.); Royal Papworth Hospital, Cambridge, UK (J.R.W.M.); Department of Radiology, Royal Infirmary of Scotland, Edinburgh, UK (A.N., E.J.R.v.B., M.C.W.); Blavatnik Family Women's Health Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY (L.J.S.); Seymour, Paul and Gloria Milstein Division of Cardiology, Department of Medicine, and Department of Radiology, Columbia University Irving Medical Center and New York-Presbyterian Hospital, New York, NY (A.J.E.); and Institute of Clinical Sciences, University of Glasgow, UK (G.R.).ORCID 0000-0003-0533-7991
David E NewbyFrom the British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, UK (J.C., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); Department of Radiology, Ninewells Hospital, Dundee, UK (P.G.R.); Clinical Research Imaging Facility, University of Dundee, UK (P.G.R.); Department of Medical Physics, NHS Lothian, Edinburgh, UK (N.W.W.); Edinburgh Imaging Facility QMRI, University of Edinburgh, Edinburgh, UK (N.W.W., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); University of Cambridge, Cambridge, UK (J.R.W.M.); Royal Papworth Hospital, Cambridge, UK (J.R.W.M.); Department of Radiology, Royal Infirmary of Scotland, Edinburgh, UK (A.N., E.J.R.v.B., M.C.W.); Blavatnik Family Women's Health Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY (L.J.S.); Seymour, Paul and Gloria Milstein Division of Cardiology, Department of Medicine, and Department of Radiology, Columbia University Irving Medical Center and New York-Presbyterian Hospital, New York, NY (A.J.E.); and Institute of Clinical Sciences, University of Glasgow, UK (G.R.).ORCID 0000-0001-7971-4628
Edwin J R van BeekFrom the British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, UK (J.C., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); Department of Radiology, Ninewells Hospital, Dundee, UK (P.G.R.); Clinical Research Imaging Facility, University of Dundee, UK (P.G.R.); Department of Medical Physics, NHS Lothian, Edinburgh, UK (N.W.W.); Edinburgh Imaging Facility QMRI, University of Edinburgh, Edinburgh, UK (N.W.W., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); University of Cambridge, Cambridge, UK (J.R.W.M.); Royal Papworth Hospital, Cambridge, UK (J.R.W.M.); Department of Radiology, Royal Infirmary of Scotland, Edinburgh, UK (A.N., E.J.R.v.B., M.C.W.); Blavatnik Family Women's Health Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY (L.J.S.); Seymour, Paul and Gloria Milstein Division of Cardiology, Department of Medicine, and Department of Radiology, Columbia University Irving Medical Center and New York-Presbyterian Hospital, New York, NY (A.J.E.); and Institute of Clinical Sciences, University of Glasgow, UK (G.R.).ORCID 0000-0002-2777-5071
Giles RoditiFrom the British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, UK (J.C., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); Department of Radiology, Ninewells Hospital, Dundee, UK (P.G.R.); Clinical Research Imaging Facility, University of Dundee, UK (P.G.R.); Department of Medical Physics, NHS Lothian, Edinburgh, UK (N.W.W.); Edinburgh Imaging Facility QMRI, University of Edinburgh, Edinburgh, UK (N.W.W., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); University of Cambridge, Cambridge, UK (J.R.W.M.); Royal Papworth Hospital, Cambridge, UK (J.R.W.M.); Department of Radiology, Royal Infirmary of Scotland, Edinburgh, UK (A.N., E.J.R.v.B., M.C.W.); Blavatnik Family Women's Health Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY (L.J.S.); Seymour, Paul and Gloria Milstein Division of Cardiology, Department of Medicine, and Department of Radiology, Columbia University Irving Medical Center and New York-Presbyterian Hospital, New York, NY (A.J.E.); and Institute of Clinical Sciences, University of Glasgow, UK (G.R.).ORCID 0000-0001-9393-7764
Michelle C WilliamsFrom the British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, UK (J.C., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); Department of Radiology, Ninewells Hospital, Dundee, UK (P.G.R.); Clinical Research Imaging Facility, University of Dundee, UK (P.G.R.); Department of Medical Physics, NHS Lothian, Edinburgh, UK (N.W.W.); Edinburgh Imaging Facility QMRI, University of Edinburgh, Edinburgh, UK (N.W.W., M.R.D., N.L.M., D.E.N., E.J.R.v.B., M.C.W.); University of Cambridge, Cambridge, UK (J.R.W.M.); Royal Papworth Hospital, Cambridge, UK (J.R.W.M.); Department of Radiology, Royal Infirmary of Scotland, Edinburgh, UK (A.N., E.J.R.v.B., M.C.W.); Blavatnik Family Women's Health Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY (L.J.S.); Seymour, Paul and Gloria Milstein Division of Cardiology, Department of Medicine, and Department of Radiology, Columbia University Irving Medical Center and New York-Presbyterian Hospital, New York, NY (A.J.E.); and Institute of Clinical Sciences, University of Glasgow, UK (G.R.).ORCID 0000-0003-3556-2428
British Heart Foundation · GBEdinburgh Royal Infirmary · GBNewYork–Presbyterian Hospital · USNHS Lothian · GBUniversity of Dundee · GB

Funding

British Heart Foundation CH/09/002/26360British Heart Foundation CH/F/21/90010British Heart Foundation FS/14/78/31020British Heart Foundation FS/ICRF/20/26002British Heart Foundation RE/18/5/34216British Heart Foundation RG/F/22/110093Wellcome TrustWellcome Trust WT103782AIA
6 · The paper itself

Abstract

Background In the Scottish Computed Tomography of the Heart (SCOT-HEART) trial in individuals with stable chest pain, a treatment strategy based on coronary CT angiography (CTA) led to improved outcomes. Purpose To assess 5-year cumulative radiation doses of participants undergoing investigation for suspected angina due to coronary artery disease with or without coronary CTA. Materials and Methods This secondary analysis of the SCOT-HEART trial included data from six of 12 recruiting sites and two of three imaging sites. Participants were recruited between November 18, 2010, and September 24, 2014, with follow-up through January 31, 2018. Study participants had been randomized (at a one-to-one ratio) to standard care with CT (

Indexed as

Coronary Artery DiseaseRadiation ExposureChest PainComputed Tomography AngiographyCoronary AngiographyHumansRadiation DosageTomography, X-Ray Computed

Identifiers

PMID37526539
PMCPMC10478793
OpenAlexW4385442619

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.