Evidence map›Paper›PMID 37526398›Full record

ArticleGut microbes

Genetic and gut microbiome determinants of SCFA circulating and fecal levels, postprandial responses and links to chronic and acute inflammation.

Ana Nogal, Francesco Asnicar, Amrita Vijay, Afroditi Kouraki, Alessia Visconti, Panayiotis Louca, Kari Wong, Andrei-Florin Baleanu, Francesca Giordano, Jonathan Wolf and 16 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Trial
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  8. Review
  9. Modulation of the gut microbiota by traditional Chinese medicine to attenuate chemotherapy-induced toxicity in gastric cancer: a review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Nutrients · 2026
    Article
  17. Article
  18. Review
  19. Article
  20. Gut microbes · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Ana NogalDepartment of Twin Research, King's College London, London, UK.
Francesco AsnicarDepartment of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy.
Amrita VijayNottingham NIHR Biomedical Research Centre at the School of Medicine, University of Nottingham, Nottingham, UK.
Afroditi KourakiNottingham NIHR Biomedical Research Centre at the School of Medicine, University of Nottingham, Nottingham, UK.
Alessia ViscontiDepartment of Twin Research, King's College London, London, UK.
Panayiotis LoucaDepartment of Twin Research, King's College London, London, UK.
Kari WongMetabolon, Metabolon, Inc. Research Triangle Park, Morrisville, NC, USA.
Andrei-Florin BaleanuDepartment of Twin Research, King's College London, London, UK.
Francesca GiordanoZoe Limited, London, UK.
Jonathan WolfZoe Limited, London, UK.
George HadjigeorgiouZoe Limited, London, UK.
Richard DaviesZoe Limited, London, UK.
Gregory A MichelottiMetabolon, Metabolon, Inc. Research Triangle Park, Morrisville, NC, USA.
Paul W FranksLund University Diabetes Center, Lund University, Malmö, Sweden.
Sarah E BerryDepartment of Nutritional Sciences, King's College London, London, UK.
Mario FalchiDepartment of Twin Research, King's College London, London, UK.
Adeel IkramNottingham NIHR Biomedical Research Centre at the School of Medicine, University of Nottingham, Nottingham, UK.
Benjamin J OllivereNottingham NIHR Biomedical Research Centre at the School of Medicine, University of Nottingham, Nottingham, UK.
Amy ZhengNottingham NIHR Biomedical Research Centre at the School of Medicine, University of Nottingham, Nottingham, UK.
Jessica NightingaleNottingham NIHR Biomedical Research Centre at the School of Medicine, University of Nottingham, Nottingham, UK.
Massimo ManginoDepartment of Twin Research, King's College London, London, UK.
Nicola SegataDepartment of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy.
William J BulsiewiczZoe Limited, London, UK.
Tim D SpectorDepartment of Twin Research, King's College London, London, UK.
Ana M ValdesNottingham NIHR Biomedical Research Centre at the School of Medicine, University of Nottingham, Nottingham, UK.
Cristina MenniDepartment of Twin Research, King's College London, London, UK.ORCID 0000-0001-9790-0571

Funding

British Heart FoundationDepartment of Health 16/61/10Department of Health NIHR132240Medical Research Council MR/M004422/1Medical Research Council MR/M016560/1Medical Research Council MR/W026813/1Wellcome TrustWellcome Trust 212904/Z/18/Z
6 · The paper itself

Abstract

Short-chain fatty acids (SCFA) are involved in immune system and inflammatory responses. We comprehensively assessed the host genetic and gut microbial contribution to a panel of eight serum and stool SCFAs in two cohorts (TwinsUK,

Indexed as

Gastrointestinal MicrobiomeFatty Acids, VolatileFecesHumansInflammationFatty Acids, Volatilegut microbiotaheritabilityinflammatory responsepostprandialShort-chain fatty acids

Identifiers

PMID37526398
PMCPMC10395212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.