Evidence map›Paper›PMID 37526383›Full record

ReviewGut microbes

Intracellular glycogen accumulation by human gut commensals as a niche adaptation trait.

Maria Esteban-Torres, Lorena Ruiz, Valerio Rossini, Ken Nally, Douwe van Sinderen

Open access · goldAbstract readReview
In one paragraph

Review in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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  12. ISME communications · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Maria Esteban-TorresAPC Microbiome Ireland, University College Cork, Cork, Ireland.
Lorena RuizDepartment of Microbiology and Biochemistry of Dairy Products, Instituto de Productos Lácteos de Asturias, IPLA-CSIC, Villaviciosa, Spain.ORCID 0000-0001-8199-5502
Valerio RossiniAPC Microbiome Ireland, University College Cork, Cork, Ireland.
Ken NallyAPC Microbiome Ireland, University College Cork, Cork, Ireland.ORCID 0000-0002-9833-170X
Douwe van SinderenAPC Microbiome Ireland, University College Cork, Cork, Ireland.ORCID 0000-0003-1823-7957
University College Cork · IEInstituto de Productos Lácteos de Asturias · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human gut microbiota is a key contributor to host metabolism and physiology, thereby impacting in various ways on host health. This complex microbial community has developed many metabolic strategies to colonize, persist and survive in the gastrointestinal environment. In this regard, intracellular glycogen accumulation has been associated with important physiological functions in several bacterial species, including gut commensals. However, the role of glycogen storage in shaping the composition and functionality of the gut microbiota offers a novel perspective in gut microbiome research. Here, we review what is known about the enzymatic machinery and regulation of glycogen metabolism in selected enteric bacteria, while we also discuss its potential impact on colonization and adaptation to the gastrointestinal tract. Furthermore, we survey the presence of such glycogen biosynthesis pathways in gut metagenomic data to highlight the relevance of this metabolic trait in enhancing survival in the highly competitive and dynamic gut ecosystem.

Indexed as

Gastrointestinal MicrobiomeMicrobiotaBacteriaGastrointestinal TractGlycogenHumansGlycogenbacteria-host interactionscarbohydrate-active enzymescolonization factorscommensal bacteriaglycogen metabolismgut microbiotamicrobiome

Identifiers

PMID37526383
PMCPMC10395257
OpenAlexW4385442179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.