Evidence map›Paper›PMID 37526373›Full record

ReviewClinical cardiology2023

LVAD therapy as a catalyst to heart failure remission and myocardial recovery.

Eman A Hamad, Mirnela Byku, Sharon B Larson, Filio Billia

Open access · goldAbstract readReview
In one paragraph

Review in Clinical cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Deactivation of LVAD support for myocardial recovery-surgical perspectives.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2024
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Eman A HamadLewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.ORCID http://orcid.org/0000-0003-1513-0310
Mirnela BykuDepartment of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
Sharon B LarsonBaptist Heart Institute at Baptist Memorial Hospital, Memphis, Tennessee, USA.
Filio BilliaPeter Munk Cardiac Center, University Health Network, Toronto, Ontario, Canada.
Baptist Memorial Hospital · USTemple University · USUniversity Health Network · CAUniversity of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of chronic heart failure over the past decade has witnessed tremendous strides in medical optimization and device therapy including the use of left ventricular assist devices (LVAD). What we once thought of as irreversible damage to the myocardium is now demonstrating signs of reverse remodeling and recovery. Myocardial recovery on the structural, molecular, and hemodynamic level is necessary for sufficient recovery to withstand explant and achieve sustained recovery post-LVAD. Guideline-directed medical therapy and unloading have been shown to aid in recovery with the potential to successfully explant the LVAD. This review will summarize medical optimization, assessment for recovery, explant methodologies and outcomes post-recovery with explant of durable LVAD.

Indexed as

Heart-Assist DevicesHeart FailureHeart VentriclesHumansMyocardiumVentricular RemodelingexplantGDMTLVADrecovery

Identifiers

PMID37526373
PMCPMC10577530
OpenAlexW4385442110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.