Evidence map›Paper›PMID 37526027›Full record

ReviewCirculation. Cardiovascular imaging2023

Noninvasive Assessment of Lipomatous Metaplasia as a Substrate for Ventricular Tachycardia in Chronic Infarct.

Lingyu Xu, Benoit Desjardins, Walter R Witschey, Saman Nazarian

Open access · greenAbstract readReview
In one paragraph

Review in Circulation. Cardiovascular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lingyu XuCardiovascular Medicine Division (L.X., S.N.), University of Pennsylvania School of Medicine, Philadelphia.ORCID 0000-0001-6145-8371
Benoit DesjardinsDepartment of Radiology (B.D., W.R.W.), University of Pennsylvania School of Medicine, Philadelphia.
Walter R WitscheyDepartment of Radiology (B.D., W.R.W.), University of Pennsylvania School of Medicine, Philadelphia.ORCID 0000-0003-1669-2120
Saman NazarianCardiovascular Medicine Division (L.X., S.N.), University of Pennsylvania School of Medicine, Philadelphia.ORCID 0000-0002-8369-0259
University of Pennsylvania · USUniversity of the Sciences · US

Funding

High Spatial and Temporal Resolution MRI Mapping of Oxygen Consumption in HumansP41EB029460 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI Ravinder Reddy · 2021 to 2026
$7.6M
Cardiac MR imaging of hemorrhagic reperfusion injury after myocardial infarctionR01HL137984 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI WITSCHEY, WALTER R.T. · 2018 to 2022
$2.8M
Implications of Intra-Myocardial Fat Deposition upon Propensity for Malignant ArrhythmiaR01HL142893 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI NAZARIAN, SAMAN, TRAYANOVA, NATALIA A. · 2018 to 2021
$2.5M
NHLBI NIH HHS R01 HL137984NHLBI NIH HHS R01 HL142893NIBIB NIH HHS P41 EB029460
6 · The paper itself

Abstract

Myocardial lipomatous metaplasia (LM) has been increasingly reported in patients with prior myocardial infarction. Cardiac magnetic resonance and cardiac contrast-enhanced computed tomography have been used to noninvasively detect and quantify myocardial LM in postinfarct patients, and may provide useful information for understanding cardiac mechanics, arrhythmia susceptibility, and prognosis. This review aims to summarize the advantages and disadvantages, clinical applications, and imaging features of different cardiac magnetic resonance sequences and cardiac contrast-enhanced computed tomography for LM detection and quantification. We also briefly summarize LM prevalence in different cohorts of postinfarct patients and review the clinical utility of cardiac imaging in exploring myocardial LM as an arrhythmogenic substrate in patients with prior myocardial infarction.

Indexed as

Myocardial InfarctionTachycardia, VentricularArrhythmias, CardiacHumansMagnetic Resonance ImagingMetaplasiaMyocardiumadipocytesintracellular spacemetaplasiamyocardial infarctionmyocardium

Identifiers

PMID37526027
PMCPMC10528518
OpenAlexW4385442414

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.