ArticleClinical interventions in aging2023
The Prognostic Value of the Age-Adjusted Charlson Comorbidity Index Among the Elderly with Breast Cancer.
Article in Clinical interventions in aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- CDK4/6 inhibitor combined with endocrine therapy: a real-world evaluation of efficacy and safety in HR+/HER2- advanced breast cancer.World journal of surgical oncology · 2026Article
- Prognostic factors and survival in elderly breast cancer patients: roles of age, stage and inflammatory markers.BMC cancer · 2026Article
- Multimodal machine learning integrates clinical and comorbidity data to predict breast cancer prognosis and treatment outcomes.Scientific reports · 2026Article
- Prognostic Evaluation of the Charlson Comorbidity Index for Breast Cancer Patients by Propensity Score Matching Analysis.Journal of breast cancer · 2026Article
- Association of comorbidity burden with initial treatment allocation in older women with gynecologic cancer: a retrospective cohort study.Frontiers in medicine · 2026Article
- Exploratory evaluation of combined handgrip strength and Age-Adjusted Charlson Comorbidity Index for prognosis in patients with primary liver cancer undergoing hepatectomy: a single-centre pilot study.Frontiers in medicine · 2026Article
- Predictors of postoperative complications in elderly patients undergoing pulmonary lobectomy: a retrospective cohort study.Frontiers in medicine · 2026Article
- Comorbidity burden in elderly high-grade glioma patients: impact on radiotherapy outcomes.BMC cancer · 2025Article
- Charlson-Deyo Index Impact on Overall Survival After Surgery for Sinonasal Squamous Cell Carcinoma.Laryngoscope investigative otolaryngology · 2025Article
- Association between the age-adjusted Charlson Comorbidity Index and complications after kidney transplantation: a retrospective observational cohort study.BMC nephrology · 2024Observational
- Risk Factor Analysis of Complications and Mortality Following Coil Procedures in Patients with Intracranial Unruptured Aneurysms Using a Nationwide Health Insurance Database.Journal of clinical medicine · 2024Article
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7 authors.
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Abstract
Purpose: This study aimed to assess the effect of comorbidities on prognosis using the Age-adjusted Charlson Comorbidity Index (ACCI) among the elderly with breast cancer (BC). Methods: This study included 745 patients divided into two groups following the ACCI score (≤3 vs >3). Multivariate logistic regression analysis was conducted for all kinds of outcomes, including BC-specific death (BCSD) and non-breast cancer-specific death (NBCSD). The Kaplan-Meier curves were plotted, and survival analysis was conducted for disease-free survival (DFS), overall survival (OS), BC-specific survival (BCSS), and non-BCSS (NBCSS). Results: A significantly higher NBCSD was found in the high-score (ACCI > 3) group than in the low-score (ACCI < 3) group ( Conclusion: ACCI was indeed an effective indicator of the effects of comorbidities on survival among elderly patients with BC. However, the co-effect from age and comorbidities was not significant enough on cancer-specific prognosis, although it exerted a significant effect on treatments received.
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