Evidence map›Paper›PMID 37525697›Full record

ArticleEuropean journal of biomedical research2023

Sequencing the SARS-CoV-2 Genome from Stool Samples of Post-acute Cases Implicates a Novel Mutation Associated with Reduced Antibody Neutralization.

Natalya Panova, Nina P Allan, Noelle C Rubas, Rosa H Lee, Braden P Kunihiro, Lesley Umeda, Rafael Peres, Ruben Juarez, Alika K Maunakea

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of biomedical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Natalya PanovaUniversity of Hawaii, USA.
Nina P AllanUniversity of Hawaii, USA.
Noelle C RubasUniversity of Hawaii, USA.
Rosa H LeeUniversity of Hawaii, USA.
Braden P KunihiroUniversity of Hawaii, USA.
Lesley UmedaUniversity of Hawaii, USA.
Rafael PeresUniversity of Hawaii, USA.
Ruben JuarezUniversity of Hawaii, USA.
Alika K MaunakeaUniversity of Hawaii, USA.

Funding

Empowering schools as community assets to mitigate the adverse impacts of COVID-19OT2HD108105 · NICHD · UNIVERSITY OF HAWAII AT MANOA · PI JUAREZ, RUBEN, MAUNAKEA, ALIKA KEOLAOKALANI · 2021 to 2022
$3.8M
Socioecological Determinants of Immunoepigenetic Signatures of Diabetes Risk in Indigenous CommunitiesR01MD016593 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI MAUNAKEA, ALIKA KEOLAOKALANI · 2021 to 2025
$3.3M
NICHD NIH HHS OT2 HD108105NIMHD NIH HHS R01 MD016593
6 · The paper itself

Abstract

Whole-genome SARS-CoV-2 sequencing tools are crucial for tracking the COVID-19 pandemic. However, current techniques require sampling of actively infectious patients following COVID-19 testing to recover enough SARS-CoV-2 RNA from the nasopharyngeal passage, which rapidly clears during the first few weeks of infection. A prospective assessment of the viral genome sourced from recovered non-infectious patients would greatly facilitate epidemiological tracking. Thus, we developed a protocol to isolate and sequence the genome of SARS-CoV-2 from stool samples of post-acute SARS-CoV-2 patients, at timepoints ranging from 10-120 days after onset of symptoms. Stool samples were collected from patients at varying timepoints post-convalescence, and viral DNA was isolated and sequenced using the QIAamp Viral RNA Mini Kit (Qiagen Inc.) and Ion Ampliseq

Indexed as

COVID-19sequencingstoolvariants

Identifiers

PMID37525697
PMCPMC10389300

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.