Evidence map›Paper›PMID 37525441›Full record

ArticleBiomacromolecules2023

Sequence-Encoded Differences in Phase Separation Enable Formation of Resilin-like Polypeptide-Based Microstructured Hydrogels.

Sai S Patkar, Cristobal Garcia Garcia, Luisa L Palmese, Kristi L Kiick

Abstract read
In one paragraph

Article in Biomacromolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Amino acid transfer free energies reveal thermodynamic driving forces in biomolecular condensate formation.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Article
  3. Engineered Protein Hydrogels as Biomimetic Cellular Scaffolds.Advanced materials (Deerfield Beach, Fla.) · 2024
    Review
  4. Review
  5. Review
  6. Article
  7. Spontaneous Self-Organized Order Emerging From Intrinsically Disordered Protein Polymers.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sai S PatkarDepartment of Materials Science and Engineering, University of Delaware, Newark, Delaware 19716, United States.ORCID 0000-0002-7763-4031
Cristobal Garcia GarciaDepartment of Materials Science and Engineering, University of Delaware, Newark, Delaware 19716, United States.ORCID 0000-0001-6724-0250
Luisa L PalmeseDepartment of Materials Science and Engineering, University of Delaware, Newark, Delaware 19716, United States.ORCID 0000-0002-8289-9261
Kristi L KiickDepartment of Materials Science and Engineering, University of Delaware, Newark, Delaware 19716, United States.ORCID 0000-0001-8587-0301

Funding

Predictive Modeling & Optimal Control Framework for Model-Based Epidemic Response in DelawareP20GM103446 · NIGMS · UNIVERSITY OF DELAWARE · PI Shawn W Polson · 2012 to 2026
$67.2M
Understanding synovial macrophage inflamm-aging within osteoarthritisP20GM139760 · NIGMS · UNIVERSITY OF DELAWARE · PI DAWN M ELLIOTT · 2021 to 2026
$19.1M
UDE COBRE: STRAINED MOLECULES FOR SYNTHESIS OF UNNATURAL AMINO ACIDSP20RR017716 · NCRR · UNIVERSITY OF DELAWARE · PI BEEBE, THOMAS PAUL · 2002 to 2011
$16.9M
Highly resilient, hydrophilic bioelastomers for engineering vocal fold tissueR01DC011377 · NIDCD · UNIVERSITY OF DELAWARE · PI KIICK, KRISTI L · 2012 to 2016
$2.3M
Acquisition of a Zeiss LSM710 Confocal MicroscopeS10RR027273 · NCRR · UNIVERSITY OF DELAWARE · PI DUNCAN, MELINDA K · 2010 to 2010
$494k
Zeiss LSM710 Inverted Confocal MicroscopeS10OD016361 · OD · UNIVERSITY OF DELAWARE · PI CAPLAN, JEFFREY L · 2015 to 2015
$444k
NCRR NIH HHS P20 RR017716NCRR NIH HHS S10 RR027273NIDCD NIH HHS R01 DC011377NIGMS NIH HHS P20 GM103446NIGMS NIH HHS P20 GM139760NIH HHS S10 OD016361
6 · The paper itself

Abstract

Microstructured hydrogels are promising platforms to mimic structural and compositional heterogeneities of the native extracellular matrix (ECM). The current state-of-the-art soft matter patterning techniques for generating ECM mimics can be limited owing to their reliance on specialized equipment and multiple time- and energy-intensive steps. Here, a photocross-linking methodology that traps various morphologies of phase-separated multicomponent formulations of compositionally distinct resilin-like polypeptides (RLPs) is reported. Turbidimetry and quantitative

Indexed as

HydrogelsRegenerative MedicineHumansInsect ProteinsPeptidesHydrogelsInsect ProteinsPeptidesresilin

Identifiers

PMID37525441
PMCPMC11661554

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.