Evidence map›Paper›PMID 37525332›Full record

ArticleACS applied materials & interfaces2023

Modulating On-Demand Release of Vancomycin from Implant Coatings via Chemical Modification of a Micrococcal Nuclease-Sensitive Oligonucleotide Linker.

Jordan D Skelly, Feiyang Chen, Shing-Yun Chang, Rewati R Ujjwal, Ananta Ghimire, David C Ayers, Jie Song

Open access · greenAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jordan D SkellyDepartment of Orthopedics and Physical Rehabilitation, UMass Chan Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655, United States.ORCID 0000-0002-1310-6555
Feiyang ChenDepartment of Orthopedics and Physical Rehabilitation, UMass Chan Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655, United States.ORCID 0000-0003-3183-246X
Shing-Yun ChangDepartment of Orthopedics and Physical Rehabilitation, UMass Chan Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655, United States.ORCID 0000-0003-2669-7574
Rewati R UjjwalDepartment of Orthopedics and Physical Rehabilitation, UMass Chan Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655, United States.ORCID 0000-0001-6016-0872
Ananta GhimireDepartment of Orthopedics and Physical Rehabilitation, UMass Chan Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655, United States.
David C AyersDepartment of Orthopedics and Physical Rehabilitation, UMass Chan Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655, United States.
Jie SongDepartment of Orthopedics and Physical Rehabilitation, UMass Chan Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655, United States.ORCID 0000-0001-7554-5564
University of Massachusetts Chan Medical School · US

Funding

Micrococcal nuclease-triggered antibiotics release: a prophylactic implant coating against S. aureus infectionsR01AR078044 · NIAMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SONG, JIE · 2020 to 2024
$2.4M
NIAMS NIH HHS R01 AR078044
6 · The paper itself

Abstract

Periprosthetic infections are one of the most serious complications in orthopedic surgeries, and those caused by

Indexed as

Staphylococcal InfectionsVancomycinAnimalsAnti-Bacterial AgentsMiceMicrococcal NucleaseRatsStaphylococcus aureusAnti-Bacterial AgentsMicrococcal NucleaseVancomycinhydrogel coatingmetal alloy implantmicrococcal nucleaseosteomyelitisperiprosthetic infectionsStaphylococcus aureusvancomycin

Identifiers

PMID37525332
PMCPMC10421633
OpenAlexW4385442722

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.