Evidence map›Paper›PMID 37525138›Full record

ArticleBMC ophthalmology2023

Clinical observation of phacoemulsification under the low perfusion pattern and low negative pressure in patients with low corneal endothelial cell density.

Yan Lin, Biting Zhou, Yihua Yao, Qin Ye, Yihua Zhu, Xiaohui Wang

Abstract read
In one paragraph

Article in BMC ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Quantitative assessment of ophthalmic viscosurgical device retention during phacoemulsification and aspiration: an ex vivo analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  3. Article
  4. Article
  5. EVA NEXUS-Phaco performance study.International journal of ophthalmology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yan LinDepartment of Ophthalmology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Biting ZhouDepartment of Ophthalmology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Yihua YaoDepartment of Ophthalmology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Qin YeDepartment of Ophthalmology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Yihua ZhuDepartment of Ophthalmology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China. zhuyihua209@163.com.
Xiaohui WangDepartment of Ophthalmology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China. wxhfyyk@163.com.

Funding

Qihang Funds of Fujian Medical University No. 2021QH1079Science and Technology Innovation joint Fund Project of Fujian Provincial Department of Science and Technology No. 2021Y9013
6 · The paper itself

Abstract

backgroundTo observe the safety and effect of phacoemulsification combined with intraocular lens (IOL) implantation in patients with low corneal endothelial cell density (CD) under the low perfusion pattern with low negative pressure.

methodsIn this retrospective case series study, a total of 16 patients (17 eyes) were studied. They had all been diagnosed with low corneal endothelial (CD) and cataracts in the First Affiliated Hospital of Fujian Medical University from December 2019 to October 2021. They underwent phacoemulsification combined with IOL implantation under the low perfusion pattern with low negative pressure. The variations of corneal endothelial( CD), coefficient of variation (CV) of the cell area, central corneal thickness (CCT), visual acuity, and intraocular pressure before and after the operation were observed and assessed. Then a paired t-test, repeated measures analysis of variance, and Pearson correlation analysis were adopted for data analysis.

resultsThe mean intraocular pressure of the 17 eyes was 16.88 ± 6.47 mmHg before the operation and 14.41 ± 3.10 mmHg after the operation, showing a statistically significant difference of t = 2.222, and p = 0.041. Before the operation, the mean visual acuity was 0.16 ± 0.09, and after the operation, it was 0.45 ± 0.16, displaying a statistically significant difference of t = -9.917, p < 0.001. Before and after the operation, four of the 17 eyes had no detectable CD. The mean CD of the other 13 eyes at one month after the operation (644.308 ± 106.24 cells/mm

conclusionsThe low perfusion pattern with low negative pressure is safe and effective for corneal endothelial dysfunction patients complicated with cataracts.

Indexed as

CataractPhacoemulsificationCell CountEndothelial CellsEndothelium, CornealHumansLens Implantation, IntraocularPerfusionRetrospective StudiesCataractCorneal endothelial cellLow perfusion patternPhacoemulsification

Identifiers

PMID37525138
PMCPMC10391892

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.