Evidence map›Paper›PMID 37524995›Full record

ArticleJournal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology2023

New bone formation accelerates during lower limb lengthening and deformity correction in children with Ollier's disease.

Chunxing Wu, Yiyong Huang, Peng Huang, Yueqiang Mo, Dahui Wang, Bo Ning

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In one paragraph

Article in Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Chunxing Wu *Department of Pediatric Orthopaedics, Children's Hospital of Fudan University, National Children's Medical Center, 201102, Shanghai, China.ORCID http://orcid.org/0000-0002-2702-5000
Yiyong Huang *Department of Pediatric Orthopaedics, Hainan Women and Children's Medical Center, Haikou, 570206, China.ORCID http://orcid.org/0000-0001-9416-5890
Peng HuangDepartment of Pediatric Orthopaedics, Children's Hospital of Fudan University, National Children's Medical Center, 201102, Shanghai, China.ORCID http://orcid.org/0000-0001-9398-0578
Yueqiang MoDepartment of Pediatric Orthopaedics, Children's Hospital of Fudan University, National Children's Medical Center, 201102, Shanghai, China.ORCID http://orcid.org/0000-0002-9096-5919
Dahui WangDepartment of Pediatric Orthopaedics, Children's Hospital of Fudan University, National Children's Medical Center, 201102, Shanghai, China.ORCID http://orcid.org/0000-0002-3101-702X
Bo NingDepartment of Pediatric Orthopaedics, Children's Hospital of Fudan University, National Children's Medical Center, 201102, Shanghai, China. ningbo@fudan.edu.cn.ORCID http://orcid.org/0000-0002-9752-2459
Children's Hospital of Fudan University · CNHainan Modern Women and Children's Hospital · CN

Funding

Science and Technology Commission of Shanghai Municipality 20Y11912900Science and Technology Commission of Shanghai Municipality 22Y11912200
6 · The paper itself

Abstract

backgroundOllier's disease can cause severe length discrepancy of the lower extremities and deformity in children. Osteotomy and limb lengthening with external fixation can correct the limb deformity. This study evaluated (1) whether the duration of external fixation was reduced in patients with Ollier's disease, and (2) the incidence of complications such as pin tract infection, external fixation loosening, and joint stiffness.

methodsTwo groups were compared with respect to age, angular correction (AC), lengthening gap (LG), distraction index (DI), lengthening length (LL), lengthening length percentage (L%), lengthening index (LI), bone healing index (BHI), and external fixation index (EFI). Group 1 (Ollier's disease) comprised nine patients undergoing 11 lower limb lengthening procedures using external fixators; group 2 (control, normal lengthened bone) comprised 28 patients undergoing 29 lengthening procedures with external fixators.

resultsIn patients with Ollier's disease, full correction of the deformity and full restoration of length were achieved in all cases. In the femur, the mean AC (15.97° vs. 6.72°) and DI (1.11 mm/day vs. 0.78 mm/day) were significantly larger, while the LI (9.71 days/cm vs. 13.49 days/cm), BHI (27.00 days/cm vs. 42.09 days/cm), and EFI (37.86 days/cm vs. 56.97 days/cm) were all significantly shorter in group 1 than in group 2 (p < 0.05). In the tibia, the mean AC and L% were larger, while the LG, LI, BHI, and EFI were all shorter in group 1 than in group 2. There was no significant difference between the two groups in the incidence of complications.

conclusionIn children with Ollier's disease, new bone formation accelerated and the healing speed of the lengthened segments was faster throughout the whole lengthening period with external fixation, and full correction of the deformity and full restoration of length could be achieved. LEVEL OF EVIDENCE III:

Indexed as

Bone LengtheningEnchondromatosisLower ExtremityOsteogenesisChildChild, PreschoolFemaleFemurHumansInfantLegLeg Length InequalityMaleTibiaTreatment OutcomeBone healing indexExternal fixationLower limb lengtheningNew bone formationOllier’s diseaseOsteotomy

Identifiers

PMID37524995
PMCPMC10390424
OpenAlexW4385429755

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.